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公开(公告)号:US20240279728A1
公开(公告)日:2024-08-22
申请号:US18568668
申请日:2022-06-08
Applicant: UTI Limited Partnership
IPC: C12Q1/6853
CPC classification number: C12Q1/6853
Abstract: The present disclosure relates to improvements in the Dinucleotide signaTurE CapTure (DTECT) method. The improved detection of a dinucleotide sequence in a target polynucleotide generally involves the steps of Acu1 digestion, heat inactivation and ligation to unique adaptors containing overhangs of two bases complementary to the dinucleotide signature.