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公开(公告)号：US06573263B2
公开(公告)日：2003-06-03
申请号：US10026310
申请日：2001-12-21
申请人： Ulrich Niewöhner , Dagmar Schauss , Martin Hendrix , Gerhard König , Frank-Gerhard Böss , Franz-Josef Van Der Staay , Rudy Schreiber , Karl-Heinz Schlemmer , Rolf Grosser
发明人： Ulrich Niewöhner , Dagmar Schauss , Martin Hendrix , Gerhard König , Frank-Gerhard Böss , Franz-Josef Van Der Staay , Rudy Schreiber , Karl-Heinz Schlemmer , Rolf Grosser
IPC分类号： C07D45704
CPC分类号： C07D487/04 , A61K31/53
摘要： The present invention relates to new substituted imidazotriazinones, processes for their preparation, and their use for the production of medicaments, in particular for improving perception, concentration power, learning power and/or memory power.
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公开(公告)号：US07022709B2
公开(公告)日：2006-04-04
申请号：US09911277
申请日：2001-07-23
申请人： Frank-Gerhard Böss , Martin Hendrix , Gerhard König , Ulrich Niewöhner , Karl-Heinz Schlemmer , Rudy Schreiber , Franz-Josef Van Der Staay , Dagmar Schauss
发明人： Frank-Gerhard Böss , Martin Hendrix , Gerhard König , Ulrich Niewöhner , Karl-Heinz Schlemmer , Rudy Schreiber , Franz-Josef Van Der Staay , Dagmar Schauss
IPC分类号： A61K31/519
CPC分类号： A61K31/505
摘要： The invention relates to the use of selective phosphodiesterase 2 (PDE 2) inhibitors for producing pharmaceuticals for improving perception, concentration, learning and/or memory.
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公开(公告)号：US20120258964A1
公开(公告)日：2012-10-11
申请号：US13412946
申请日：2012-03-06
申请人： Joachim Luithle , Frank-Gerhard Böss , Christina Erb , Frank-Thorsten Hafner , Katrin Schnizler , Timo Flessner , Marja Van Kampen , Franz-Josef Van Der Staay
发明人： Joachim Luithle , Frank-Gerhard Böss , Christina Erb , Frank-Thorsten Hafner , Katrin Schnizler , Timo Flessner , Marja Van Kampen , Franz-Josef Van Der Staay
IPC分类号： C07D453/02 , A61K31/5377 , A61P25/28 , A61K31/506 , A61P25/00 , A61K31/439 , A61K31/496
CPC分类号： C07D453/02
摘要： The invention relates to novel 2-heteroaryl carboxamides and to the use thereof for producing medicaments for the treatment and/or prophylaxis of diseases and for improving perception, concentration, learning and/or memory.
摘要翻译： 本发明涉及新的2-杂芳基羧酰胺及其用于制备用于治疗和/或预防疾病和改善感知，浓度，学习和/或记忆的药物的用途。
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公开(公告)号：US20110263591A1
公开(公告)日：2011-10-27
申请号：US13179957
申请日：2011-07-11
申请人： Joachim Luithle , Frank-Gerhard Böss , Christina Erb , Frank-Thorsten Hafner , Katrin Schnizler , Timo Flessner , Marja van Kampen , Franz-Josef van der Staay
发明人： Joachim Luithle , Frank-Gerhard Böss , Christina Erb , Frank-Thorsten Hafner , Katrin Schnizler , Timo Flessner , Marja van Kampen , Franz-Josef van der Staay
IPC分类号： A61K31/439 , A61K31/506 , A61P25/28 , A61K31/5377
CPC分类号： C07D453/02
摘要： The invention relates to novel 2-heteroaryl carboxamides and to the use thereof for producing medicaments for the treatment and/or prophylaxis of diseases and for improving perception, concentration, learning and/or memory.
摘要翻译： 本发明涉及新的2-杂芳基羧酰胺及其用于制备用于治疗和/或预防疾病和改善感知，浓度，学习和/或记忆的药物的用途。
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5.发明申请AZABICYCLIC CARBAMATES AND THEIR USE AS ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR AGONISTS 有权异丁烯酸碳酸酯及其作为ALPHA-7 NICOTINIC乙酰胆碱受体激动剂公开(公告)号：US20100324085A1
公开(公告)日：2010-12-23
申请号：US12871495
申请日：2010-08-30
申请人： Timo Flessner , Frank-Gerhard Böss , Christina Erb , Frank-Thorsten Hafner , Katrin Schnizler , Dieter Lang , Joachim Luithle , Maria-Van Kampen , Franz-Josef Van der Staay
发明人： Timo Flessner , Frank-Gerhard Böss , Christina Erb , Frank-Thorsten Hafner , Katrin Schnizler , Dieter Lang , Joachim Luithle , Maria-Van Kampen , Franz-Josef Van der Staay
IPC分类号： A61K31/4375 , C07D453/02 , A61P25/00
CPC分类号： C07D453/02
摘要： The invention relates to novel benzothiophene-, benzofuran-, and indole ureas and to the use thereof for producing medicaments for the treatment and/or prophylaxis of diseases and for improving perception, concentration, learning, and/or memory.
摘要翻译： 本发明涉及新的苯并噻吩 - ，苯并呋喃和吲哚脲，以及其用于制备用于治疗和/或预防疾病和改善感知，集中，学习和/或记忆的药物的用途。
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6.发明申请公开(公告)号：US20130060039A1
公开(公告)日：2013-03-07
申请号：US13441407
申请日：2012-04-06
申请人： Timo Flessner , Frank-Gerhard Böss , Christina Erb , Frank-Thorsten Hafner , Katrin Schnizler , Dieter Lang , Joachim Luithle , Marja Van Kampen , Franz-Josef van der Staay
发明人： Timo Flessner , Frank-Gerhard Böss , Christina Erb , Frank-Thorsten Hafner , Katrin Schnizler , Dieter Lang , Joachim Luithle , Marja Van Kampen , Franz-Josef van der Staay
IPC分类号： C07D453/02
CPC分类号： C07D453/02
摘要： The invention relates to novel benzothiophene-, benzofuran-, and indole ureas and to the use thereof for producing medicaments for the treatment and/or prophylaxis of diseases and for improving perception, concentration, learning, and/or memory.
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公开(公告)号：US07256288B2
公开(公告)日：2007-08-14
申请号：US10496404
申请日：2002-11-06
申请人： Martin Hendrix , Frank-Gerhard Böss , Christina Erb , Joachim Krüger , Joachim Luithle , Christoph Methfessel , Rudy Schreiber , Welf-Burkhard Wiese
发明人： Martin Hendrix , Frank-Gerhard Böss , Christina Erb , Joachim Krüger , Joachim Luithle , Christoph Methfessel , Rudy Schreiber , Welf-Burkhard Wiese
IPC分类号： C07D239/02 , C07D453/02
CPC分类号： C07D453/02
摘要： The invention relates to novel heteroaryl carboxamides, a process for their preparation, and pharmaceutical compositions containing them. These materials are useful for the treatment and/or prophylaxis of diseases and for improving perception, concentration, learning and/or memory.
摘要翻译： 本发明涉及新颖的杂芳基羧酰胺，其制备方法和含有它们的药物组合物。 这些材料可用于治疗和/或预防疾病和改善感知，集中，学习和/或记忆。
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8.发明授权公开(公告)号：US08455502B2
公开(公告)日：2013-06-04
申请号：US12769166
申请日：2010-04-28
IPC分类号： A61K31/59 , A61K31/415
CPC分类号： C07D487/04 , A61K31/519 , C07D473/30
摘要： The invention relates to the use of selective phosphodiesterase 9A (PDE9A) inhibitors for producing medicaments for improving perception, concentration, cognitive processes, learning and/or memory.
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9.发明授权Selective phosphodiesterase 9A inhibitors as medicaments for improving cognitive processes 有权选择性磷酸二酯酶9A抑制剂作为改善认知过程的药物公开(公告)号：US09067945B2
公开(公告)日：2015-06-30
申请号：US13886850
申请日：2013-05-03
IPC分类号： A61K31/59 , A61K31/415 , C07D487/04 , A61K31/519 , C07D473/30
CPC分类号： C07D487/04 , A61K31/519 , C07D473/30
摘要： The invention relates to the use of selective phosphodiesterase 9A (PDE9A) inhibitors for producing medicaments for improving perception, concentration, cognitive processes, learning and/or memory.
摘要翻译： 本发明涉及选择性磷酸二酯酶9A（PDE9A）抑制剂用于制备用于改善感知，浓度，认知过程，学习和/或记忆的药物的用途。
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10.发明申请SELECTIVE PHOSPHODIESTERASE 9A INHIBITORS AS MEDICAMENTS FOR IMPROVING COGNITIVE PROCESSES 审中-公开选择性磷酸二酯酶9A抑制剂作为改善认知过程的药物公开(公告)号：US20130245045A1
公开(公告)日：2013-09-19
申请号：US13886850
申请日：2013-05-03
IPC分类号： C07D487/04
CPC分类号： C07D487/04 , A61K31/519 , C07D473/30
摘要： The invention relates to the use of selective phosphodiesterase 9A (PDE9A) inhibitors for producing medicaments for improving perception, concentration, cognitive processes, learning and/or memory.
摘要翻译： 本发明涉及选择性磷酸二酯酶9A（PDE9A）抑制剂用于制备用于改善感知，浓度，认知过程，学习和/或记忆的药物的用途。
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