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公开(公告)号:US09586973B2
公开(公告)日:2017-03-07
申请号:US14858350
申请日:2015-09-18
Applicant: Universiteit Gent
Inventor: Marc Bracke , Matthias D'hooghe , Rob De Vreese
IPC: C07D495/04 , A61K31/407 , A61K45/06
CPC classification number: C07D495/04 , A61K31/407 , A61K45/06 , Y02A50/411
Abstract: Histone deacetylases 6 (HDAC6) inhibitors and compositions containing the same. Methods of treating diseases and conditions wherein inhibition of HDAC6 provides a benefit, like a cell proliferative disease, an autoimmune or inflammatory disorder, a neurodegenerative disease, a viral disease, malaria, or a combination thereof.
Abstract translation: 组蛋白脱乙酰酶6(HDAC6)抑制剂和含有它们的组合物。 治疗疾病和病症的方法,其中HDAC6的抑制提供益处,如细胞增殖性疾病,自身免疫性或炎性疾病,神经变性疾病,病毒性疾病,疟疾或其组合。