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公开(公告)号：US10607738B2
公开(公告)日：2020-03-31
申请号：US15154307
申请日：2016-05-13
Applicant: University Health Network , Sunnybrook Research Institute
Inventor： Sean Davidson , Michael D. Sherar , Kieran Murphy , Claire McCann , Robert Weersink
Abstract: Various embodiments are described herein for a system and a method for treatment planning for providing ablative therapy to a patient. The treatment planning may involve segmenting images of the patient to define areas to receive treatment, defining trial parameters, simulating treatment of ablative therapy to the patient according to the trial parameters; analyzing a thermal dose distribution resulting from the simulated treatment to determine treatment effectiveness; determining when the treatment effectiveness meets a treatment effectiveness criteria; and providing an indication of the trial parameters when the treatment effectiveness meets the treatment effectiveness criteria.
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公开(公告)号：US20170319719A1
公开(公告)日：2017-11-09
申请号：US15661125
申请日：2017-07-27
Applicant: UNIVERSITY HEALTH NETWORK
Inventor： Gang Zheng , Elizabeth Huynh , Kenneth Ng , Mojdeh Shakiba , Robert Weersink , Brian Wilson
CPC classification number: A61K49/227 , A61K49/0036 , A61K49/0052 , A61K49/0084 , A61K49/221
Abstract: There is provided herein a nanovesicle having a bilayer comprising a saturated first phospholipid and no more than about 15 molar % of a second phospholipid covalently conjugated to a J-aggregate forming dye.
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3.发明申请SYSTEM AND METHOD FOR MINIMALLY INVASIVE THERMAL ABLATION TREATMENT PLANNING 审中-公开用于微型入侵热处理计划的系统和方法公开(公告)号：US20160335413A1
公开(公告)日：2016-11-17
申请号：US15154307
申请日：2016-05-13
Applicant: University Health Network
Inventor： Sean Davidson , Michael D. Sherar , Kieran Murphy , Claire McCann , Robert Weersink
CPC classification number: G16H50/50 , A61B34/00 , A61B2018/00577 , A61B2034/101
Abstract: Various embodiments are described herein for a system and a method for treatment planning for providing ablative therapy to a patient. The treatment planning may involve segmenting images of the patient to define areas to receive treatment, defining trial parameters, simulating treatment of ablative therapy to the patient according to the trial parameters; analyzing a thermal dose distribution resulting from the simulated treatment to determine treatment effectiveness; determining when the treatment effectiveness meets a treatment effectiveness criteria; and providing an indication of the trial parameters when the treatment effectiveness meets the treatment effectiveness criteria.
Abstract translation: 本文描述了用于为患者提供消融治疗的治疗计划的系统和方法。 治疗计划可以包括分割患者的图像以界定接受治疗的区域，定义试验参数，根据试验参数模拟对患者的消融治疗的治疗; 分析由模拟治疗产生的热剂量分布，以确定治疗有效性; 确定治疗有效性何时达到治疗有效性标准; 并且当治疗效果满足治疗有效性标准时提供试验参数的指示。
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公开(公告)号：US20150359912A1
公开(公告)日：2015-12-17
申请号：US14764403
申请日：2014-01-28
Applicant: UNIVERSITY HEALTH NETWORK
Inventor： Gang Zheng , Elizabeth Huynh , Kenneth Ng , Mojdeh Shakiba , Robert Weersink , Brian Wilson
CPC classification number: A61K49/227 , A61K49/0036 , A61K49/0052 , A61K49/0084 , A61K49/221
Abstract: There is provided herein a nanovesicle having a bilayer comprising a saturated first phospholipid and no more than about 15 molar % of a second phospholipid covalently conjugated to a J-aggregate forming dye.
Abstract translation: 本文提供了具有包含饱和第一磷脂和不超过约15摩尔％的与J-骨料形成染料共价缀合的第二磷脂的双层的纳米囊。
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