公开(公告)号：US20210003528A1

公开(公告)日：2021-01-07

申请号：US17025664

申请日：2020-09-18

Applicant: University of Florida Research Foundation, Inc.

Inventor： Josephine F. Esquivel-Upshaw ,  Fan Ren ,  Stephen J. Pearton ,  Steven Craig Ghivizzani ,  Samira Afonso Camargo ,  Chaker Fares ,  Minghan Xian ,  Patrick H. Carey ,  Jenshan Lin ,  Siang-Sin Shan ,  Yu-Te Liao ,  Shao-Yung Lu

IPC: G01N27/414 ,  B01L3/00 ,  C12Q1/6825

Abstract: Various examples are provided for disposable medical sensors that can be used for detection of SARS-CoV-2 antigen, cardiac troponin I, or other biosensing applications. In one example, a medical sensing system includes single-use disposable test strip comprising a functionalized sensing area configured to detect SARS-CoV-2 antigen and a portable sensing and readout device including pulse generation circuitry that can generate synchronized gate and drain pulses for detection and quantification of SARS-CoV-2 antigen in biological samples. In another example, a method includes providing a saliva sample to a functionalized sensing area configured to detect SARS-CoV-2 antigen, generating synchronized gate and drain pulses for a transistor, the gate pulse provided via electrodes of the functionalized sensing area, and sensing an output of the transistor that is a function of a concentration of SARS-CoV-2 antigen in the sample.