公开(公告)号：US20180142194A1

公开(公告)日：2018-05-24

申请号：US15571866

申请日：2016-05-07

Applicant: University of Florida Research Foundation, Inc.

Inventor： WALLACE GREGORY SAWYER ,  THOMAS ETTOR ANGELINI ,  STEVEN CRAIG GHIVIZZANI ,  TAPOMOY BHATTACHARJEE ,  GLYN DANIEL PALMER

IPC: C12M3/00 ,  C12M1/12 ,  C12M1/42 ,  C12N5/00

CPC classification number: C12M21/08 ,  C12M25/14 ,  C12M25/16 ,  C12M35/04 ,  C12N5/0062 ,  C12N2513/00 ,  C12N2527/00 ,  C12N2533/30 ,  C12N2535/00

Abstract: A three-dimensional cell growth medium is described. The cell growth medium may comprise hydrogel particles swollen with a liquid cell growth medium to form a granular gel yield stress material which undergoes a phase transformation from a solid phase to a liquid-like phase when an applied stress exceeds the yield stress. Cells may be placed in the three-dimensional cell growth medium according to any shape or geometry, and may remain in place within the three-dimensional cell growth medium.

公开(公告)号：US20220333051A1

公开(公告)日：2022-10-20

申请号：US17841917

申请日：2022-06-16

Applicant: University of Florida Research Foundation, Inc.

Inventor： WALLACE GREGORY SAWYER ,  THOMAS ETTOR ANGELINI ,  STEVEN CRAIG GHIVIZZANI ,  TAPOMOY BHATTACHARJEE ,  GLYN DANIEL PALMER

IPC: C12M3/00 ,  C12N5/00 ,  C12M1/12 ,  C12M1/42

Abstract: A three-dimensional cell growth medium is described. The cell growth medium may comprise hydrogel particles swollen with a liquid cell growth medium to form a granular gel yield stress material which undergoes a phase transformation from a solid phase to a liquid-like phase when an applied stress exceeds the yield stress. Cells may be placed in the three-dimensional cell growth medium according to any shape or geometry, and may remain in place within the three-dimensional cell growth medium.