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公开(公告)号:US20220145308A1
公开(公告)日:2022-05-12
申请号:US17433631
申请日:2020-03-10
Inventor: Valerie Anne De Crecy , Geoffrey Jean Hutinet
Abstract: The present disclosure is directed to materials and methods for reducing heterologous DNA damage in bacteria (i.e., induce resistance to host restriction enzymes) by modifying the heterologous DNA to include one or more deazapurine bases.