公开(公告)号：US20190231902A1

公开(公告)日：2019-08-01

申请号：US16312277

申请日：2017-06-21

申请人： University of Florida Research Foundation, Incorporated ,  Board of Supervisors of Louisiana State University & Agricultural & Mechanical College

发明人： David C. Bloom ,  Alfred S. Lewin ,  Donna M. Neumann ,  Zachary L. Watson ,  Sonal Sanjeev Tuli ,  Gregory Scott Schultz

IPC分类号： A61K48/00 ,  C12N5/0793 ,  C12N15/86 ,  C12N15/113 ,  A61P31/22

CPC分类号： A61K48/0091 ,  A61P31/22 ,  C12N5/062 ,  C12N15/1133 ,  C12N15/86 ,  C12N2310/121 ,  C12N2310/20 ,  C12N2320/32 ,  C12N2510/00 ,  C12N2750/14122 ,  C12N2750/14143 ,  C12N2750/14145

摘要： Aspects of the application relate to methods and compositions for delivering therapeutic nucleic acids to neural cells or tissue in a subject. Additional aspects of the application relate to therapeutic nucleic acids, for example therapeutic ribozymes, that are useful for inhibiting viral reactivation in a subject.

公开(公告)号：US20220380808A1

公开(公告)日：2022-12-01

申请号：US17738987

申请日：2022-05-06

申请人： University of Florida Research Foundation, Incorporated ,  Board of Supervisors of Louisiana State University & Agricultural & Mechanical College

发明人： David C. Bloom ,  Alfred S. Lewin ,  Donna M. Newmann ,  Zachary L. Watson ,  Sonal Sanjeev Tuli ,  Gregory Scott Schultz

IPC分类号： C12N15/861 ,  A61P31/22

摘要： Aspects of the application relate to methods and compositions for delivering therapeutic nucleic acids to neural cells or tissue in a subject. Additional aspects of the application relate to therapeutic nucleic acids, for example therapeutic ribozymes, that are useful for inhibiting viral reactivation in a subject.

公开(公告)号：US11351273B2

公开(公告)日：2022-06-07

申请号：US16312277

申请日：2017-06-21

申请人： University of Florida Research Foundation, Incorporated ,  Board of Supervisors Of Louisiana State University & Agricultural & Mechanical College

发明人： David C. Bloom ,  Alfred S. Lewin ,  Donna M. Neumann ,  Zachary L. Watson ,  Sonal Sanjeev Tuli ,  Gregory Scott Schultz

IPC分类号： C07H21/04 ,  A61K48/00 ,  C12N15/113 ,  C12N15/86 ,  A61P31/22 ,  C12N5/0793

摘要： Aspects of the application relate to methods and compositions for delivering therapeutic nucleic acids to neural cells or tissue in a subject. Additional aspects of the application relate to therapeutic nucleic acids, for example therapeutic ribozymes, that are useful for inhibiting viral reactivation in a subject.