公开(公告)号：US20180066279A9

公开(公告)日：2018-03-08

申请号：US15306543

申请日：2015-04-24

Applicant: University of Massachusetts

Inventor： Guangping Gao ,  Phillip D. Zamore ,  Shaoyong Li

IPC: C12N15/86 ,  C12N15/113 ,  C12N7/00 ,  C12N15/117 ,  A61K48/00 ,  A61K38/51 ,  A61K38/17 ,  A61K38/44 ,  A61K38/28 ,  A61K38/48 ,  C07K16/28 ,  C07K16/32 ,  C07K16/22 ,  C07K16/10

CPC classification number: C12N15/86 ,  A61K38/1709 ,  A61K38/28 ,  A61K38/446 ,  A61K38/4846 ,  A61K38/51 ,  A61K48/0008 ,  C07K16/10 ,  C07K16/22 ,  C07K16/2875 ,  C07K16/2887 ,  C07K16/32 ,  C12N7/00 ,  C12N15/113 ,  C12N15/117 ,  C12N2310/141 ,  C12N2310/17 ,  C12N2320/30 ,  C12N2330/51 ,  C12N2710/10322 ,  C12N2710/10332 ,  C12N2750/14143 ,  C12N2760/00042 ,  C12N2830/008 ,  C12Y115/01001 ,  C12Y304/21022 ,  C12Y401/01028 ,  C12N2310/113 ,  C12N2310/13

Abstract: The disclosure in some aspects, relates to nucleic acids, compositions and kits useful for gene therapy with reduced immune response to transgene products.

公开(公告)号：US20210317475A1

公开(公告)日：2021-10-14

申请号：US17193030

申请日：2021-03-05

Applicant: University of Massachusetts

Inventor： Guangping Gao ,  Phillip D. Zamore ,  Shaoyong Li

IPC: C12N15/86 ,  C12N15/113 ,  A61K38/17 ,  A61K38/28 ,  A61K38/44 ,  A61K38/48 ,  A61K38/51 ,  A61K48/00 ,  C07K16/10 ,  C07K16/22 ,  C07K16/28 ,  C07K16/32 ,  C12N7/00 ,  C12N15/117

Abstract: The disclosure in some aspects, relates to nucleic acids, compositions and kits useful for gene therapy with reduced immune response to transgene products.

公开(公告)号：US10975391B2

公开(公告)日：2021-04-13

申请号：US15306543

申请日：2015-04-24

Applicant: University of Massachusetts

Inventor： Guangping Gao ,  Phillip D. Zamore ,  Shaoyong Li

IPC: C12N15/86 ,  C12N15/113 ,  A61K31/713 ,  C12N7/00 ,  C12N15/117 ,  A61K38/17 ,  A61K38/28 ,  A61K38/44 ,  A61K38/48 ,  A61K38/51 ,  A61K48/00 ,  C07K16/10 ,  C07K16/22 ,  C07K16/28 ,  C07K16/32

Abstract: The disclosure in some aspects, relates to nucleic acids, compositions and kits useful for gene therapy with reduced immune response to transgene products.

公开(公告)号：US20170166925A1

公开(公告)日：2017-06-15

申请号：US15306543

申请日：2015-04-24

Applicant: University of Massachusetts

Inventor： Guangping Gao ,  Phillip D. Zamore ,  Shaoyong Li

IPC: C12N15/86 ,  C12N7/00 ,  C12N15/117 ,  A61K48/00 ,  A61K38/51 ,  C07K16/10 ,  A61K38/44 ,  A61K38/28 ,  A61K38/48 ,  C07K16/28 ,  C07K16/32 ,  C07K16/22 ,  C12N15/113 ,  A61K38/17

CPC classification number: C12N15/86 ,  A61K38/1709 ,  A61K38/28 ,  A61K38/446 ,  A61K38/4846 ,  A61K38/51 ,  A61K48/0008 ,  C07K16/10 ,  C07K16/22 ,  C07K16/2875 ,  C07K16/2887 ,  C07K16/32 ,  C12N7/00 ,  C12N15/113 ,  C12N15/117 ,  C12N2310/141 ,  C12N2310/17 ,  C12N2320/30 ,  C12N2330/51 ,  C12N2710/10322 ,  C12N2710/10332 ,  C12N2750/14143 ,  C12N2760/00042 ,  C12N2830/008 ,  C12Y115/01001 ,  C12Y304/21022 ,  C12Y401/01028 ,  C12N2310/113 ,  C12N2310/13

Abstract: The disclosure in some aspects, relates to nucleic acids, compositions and kits useful for gene therapy with reduced immune response to transgene products.