公开(公告)号：US11572417B2

公开(公告)日：2023-02-07

申请号：US16870829

申请日：2020-05-08

申请人： University of Rhode Island Board of Trustees

发明人： Teresa L. Mako ,  Mindy Levine ,  Jason Dwyer

IPC分类号： C08B15/00 ,  G01N21/78 ,  G01N31/22 ,  G01N21/25 ,  G01N21/17

摘要： The invention provides a mild procedure for the functionalization of cellulose and other substrates with a detection reagent such as N-(1-naphthyl)ethylenediamine and is able to achieve much higher functionalization density than previously reported. A paper-based device created using cellulose functionalized according to the invention allowed for much lower detection limits for nitrite in various kinds of water samples than have been seen using paper-based devices. In addition, grafting of N-(1-naphthyl)ethylenediamine to cellulose improved the stability of the N-(1-naphthyl)ethylenediamine in the presence of moisture and light.