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1.发明申请公开(公告)号：US20210138251A1
公开(公告)日：2021-05-13
申请号：US17090685
申请日：2020-11-05
发明人： David Bjanes , Chet T. Moritz
摘要： Systems and methods for delivering sensory feedback to the cortex via electrical stimulation are disclosed herein. In one embodiment, the system includes: an implant electrically coupled to a brain, a spinal cord or peripheral nerves of the user through implant electrodes. The implant is configured to deliver electrical stimulus through the implant electrodes. The system also includes a computing device that performs actions including: delivering the electrical stimulus via the implant electrodes; and generating neural signals that are evoked by the electrical stimulus. The neural signals correspond to information transferred to the brain, spinal cord or peripheral nerves through the implant electrodes. The electrical stimulus is encoded as a combination of at least two parameters selected from a group of parameters consisting of a frequency, a pulse-width, an amplitude, a number of pulses in a train, and a train interval.
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公开(公告)号：US11617887B2
公开(公告)日：2023-04-04
申请号：US16389823
申请日：2019-04-19
摘要： Systems and methods for promoting neuroplasticity in a brain of a subject to improve and/or restore neural function are disclosed herein. One such method includes detecting residual movement and/or muscular activity in a limb of the subject, such as a paretic limb. The method further includes generating a stimulation pattern based on the detected movement and/or muscular activity, and stimulating the brain of the subject with the stimulation pattern. It is expected that delivering stimulation based on the detected residual movement and/or muscular activity of the limb will induce neuroplasticity for restoring neural function, such as control of the limb. A second method involves detecting brain signals and delivering contingent stimulation. A third method involves delivering pairs of successive stimulus patterns to two brain sites, controlled either by preprogrammed sequences or contingent on neural or muscular activity or movement.
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3.发明申请公开(公告)号：US20190321639A1
公开(公告)日：2019-10-24
申请号：US16389823
申请日：2019-04-19
摘要： Systems and methods for promoting neuroplasticity in a brain of a subject to improve and/or restore neural function are disclosed herein. One such method includes detecting residual movement and/or muscular activity in a limb of the subject, such as a paretic limb. The method further includes generating a stimulation pattern based on the detected movement and/or muscular activity, and stimulating the brain of the subject with the stimulation pattern. It is expected that delivering stimulation based on the detected residual movement and/or muscular activity of the limb will induce neuroplasticity for restoring neural function, such as control of the limb. A second method involves detecting brain signals and delivering contingent stimulation. A third method involves delivering pairs of successive stimulus patterns to two brain sites, controlled either by preprogrammed sequences or contingent on neural or muscular activity or movement.
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