公开(公告)号：US20250049843A1

公开(公告)日：2025-02-13

申请号：US18723132

申请日：2022-12-21

Applicant: University of Washington

Inventor： Miqin ZHANG ,  Peter A. CHIARELLI ,  Richard REVIA ,  Zachary STEPHEN ,  Forrest M. KIEVIT ,  Kui WANG ,  Richard G. ELLENBOGEN

IPC: A61K33/26 ,  A61K41/00 ,  A61N5/10 ,  B82Y5/00

Abstract: Method for nanoparticle-mediated deposition of radiation (NMDR) and targeted radiation therapies using a biodegradable and bioabsorbable iron oxide nanoparticle with a biocompatible coating that is effective to overcome various extra- and intra-cellular barriers and selectively accumulate in solid and metastatic tumors to improve the energy transfer of conventional radiotherapy