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公开(公告)号：US09439863B2
公开(公告)日：2016-09-13
申请号：US14376907
申请日：2013-02-08
IPC分类号： A61K9/16 , A61K31/7072 , A61K9/50 , A61K9/00 , A61K9/20
CPC分类号： A61K9/1652 , A61K9/0034 , A61K9/1647 , A61K9/1658 , A61K9/2077 , A61K9/5031 , A61K31/7072
摘要： This invention relates to pharmaceutical dosage forms, particularly to pH dependent pharmaceutical dosage forms with enhanced and/or prolonged distribution of a pharmaceutical compound at a target site. More specifically, this invention relates to a controlled release intravaginal pharmaceutical dosage form and, more particularly, to a pharmaceutical dosage form which comprises microspheres encapsulated and/or embedded within a bioerodible polymeric matrix, together the microspheres and the matrix are formed into a caplet and/or tablet.
摘要翻译： 本发明涉及药物剂型，特别是涉及具有药物化合物在靶位点的增强和/或延长分布的pH依赖性药物剂型。 更具体地，本发明涉及控释型阴道内药物剂型，更具体地涉及药物剂型，其包含包封和/或嵌入生物可腐蚀的聚合物基质内的微球，所述微球和所述基质一起形成囊片和 /或平板电脑。
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公开(公告)号：US20150004225A1
公开(公告)日：2015-01-01
申请号：US14376907
申请日：2013-02-08
IPC分类号： A61K9/16 , A61K31/7072 , A61K9/50
CPC分类号： A61K9/1652 , A61K9/0034 , A61K9/1647 , A61K9/1658 , A61K9/2077 , A61K9/5031 , A61K31/7072
摘要： This invention relates to pharmaceutical dosage forms, particularly to pH dependent pharmaceutical dosage forms with enhanced and/or prolonged distribution of a pharmaceutical compound at a target site. More specifically, this invention relates to a controlled release intravaginal pharmaceutical dosage form and, more particularly, to a pharmaceutical dosage form which comprises microspheres encapsulated and/or embedded within a bioerodible polymeric matrix, together the microspheres and the matrix are formed into a caplet and/or tablet.
摘要翻译： 本发明涉及药物剂型，特别是涉及具有药物化合物在靶位点的增强和/或延长分布的pH依赖性药物剂型。 更具体地，本发明涉及控释型阴道内药物剂型，更具体地涉及药物剂型，其包含包封和/或嵌入生物可腐蚀的聚合物基质内的微球，所述微球和所述基质一起形成囊片和 /或平板电脑。
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