公开(公告)号：US20170252355A1

公开(公告)日：2017-09-07

申请号：US15517395

申请日：2015-10-13

Applicant: VIRGINIA COMMONWEALTH UNIVERSITY

Inventor： Shunlin REN ,  Jin Koung KIM

IPC: A61K31/56 ,  A61K31/58 ,  A61K31/575

CPC classification number: A61K31/56 ,  A61K31/575 ,  A61K31/58 ,  G01N2800/044

Abstract: Methods and compositions are provided for the prevention and/or treatment of symptoms associated with lipid accumulation disorders caused by attenuated leptin activity and by lipid storage disorders. The methods involve administering at least one oxygenated cholesterol sulfate (OCS) to a subject with the disorder. The disorder may be acquired or congenital (hereditary).

公开(公告)号：US20190083509A1

公开(公告)日：2019-03-21

申请号：US16108286

申请日：2018-08-22

Applicant: VIRGINIA COMMONWEALTH UNIVERSITY

Inventor： Shunlin REN ,  Jin Koung KIM

IPC: A61K31/56 ,  A61K31/575 ,  A61K31/58

Abstract: Methods and compositions are provided for the prevention and/or treatment of symptoms associated with lipid accumulation disorders caused by attenuated leptin activity and by lipid storage disorders. The methods involve administering at least one oxygenated cholesterol sulfate (OCS) to a subject with the disorder. The disorder may be acquired or congenital (hereditary).