公开(公告)号：US11325917B2

公开(公告)日：2022-05-10

申请号：US17003356

申请日：2020-08-26

Applicant: Valo Health, Inc.

Inventor： David Joseph Guerin ,  Kenneth W. Bair ,  Justin A. Caravella ,  Stephanos Ioannidis ,  David R. Lancia, Jr. ,  Hongbin Li ,  Steven Mischke ,  Pui Yee Ng ,  David Richard ,  Shawn E. R. Schiller ,  Tatiana Shelekhin ,  Zhongguo Wang

IPC: C07D495/04

Abstract: The disclosure relates to inhibitors of USP28 and/or USP25 useful in the treatment of cancers, inflammation, autoimmune diseases, and infectious diseases, having the Formula: (I), where R1, R2, R3, R4, R4′, R5, R6, X, and n are described herein.