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公开(公告)号：US20230095485A1
公开(公告)日：2023-03-30
申请号：US17485794
申请日：2021-09-27
发明人： Elena Czeizler , Mikko Hakala , Shahab Basiri , Hannu Laaksonen , Maria Isabel Cordero Marcos , Christopher Boylan , Jarkko Y. Peltola , Ville Pietilä , Esa Kuusela
摘要： A radiation treatment plan three-dimensional dose prediction machine learning model is trained using a training corpus that includes a plurality of radiation treatment plans that are not specific to a particular patient and wherein the training corpus includes some, but not all, possible patient volumes of interest. Information regarding the patient (including information regarding at least one volume of interest for the patient that was not represented in the training corpus) is input to the radiation treatment plan three-dimensional dose prediction machine model. The latter generates predicted three-dimensional dose distributions that include a predicted three-dimensional dose distribution for the at least one volume of interest that was not represented in the training corpus.
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2.发明授权公开(公告)号：US11878184B2
公开(公告)日：2024-01-23
申请号：US17322735
申请日：2021-05-17
发明人： Corey Zankowski , Janne Nord , Maria Isabel Cordero Marcos , Joona Hartman , Jarkko Peltola , Esa Kuusela
IPC分类号： A61N5/10
CPC分类号： A61N5/1031
摘要： A system for estimating a dose from a radiation therapy plan includes a memory that stores machine-readable instructions and a processor communicatively coupled to the memory, the processor operable to execute the instructions to subdivide a representation of a volume of interest into voxels. The processor also determines distances between a planned radiation field origin and each respective voxel. The processor further computes geometry-based expected (GED) metrics based on the distances, a plan parameter, and a field strength parameter. The processor sums the metrics to yield an estimated dose received by the volume of interest from the planned radiation field.
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3.发明申请Method and Apparatus for Using a Designated Patient Structure as an Area to be Masked From Radiation 审中-公开使用指定患者结构作为要从辐射掩蔽的区域的方法和装置公开(公告)号：US20140275702A1
公开(公告)日：2014-09-18
申请号：US14040095
申请日：2013-09-27
IPC分类号： A61N5/10
CPC分类号： A61N5/1001 , A61N5/1031 , A61N5/1038 , A61N5/1047 , A61N5/1048 , A61N5/1064
摘要： A control circuit provides a user with an opportunity to designate one or more patient structures for a particular patient that are to be protected from radiation. When optimizing a radiation-treatment plan for that patient, then, the control circuit uses the designated patient structure(s) as an area to be masked from radiation during administration of the radiation-treatment plan. By one approach the aforementioned opportunity to designate patient structures as being designated patient structures comprises providing the user with an opportunity to so designate patient structures via a display. The aforementioned masking can be accomplished as desired including by appropriate use of a multi-leaf collimator.
摘要翻译： 控制电路为用户提供指定要被保护免受辐射的特定患者的一个或多个患者结构的机会。 当优化该患者的放射治疗计划时，控制电路在给予辐射治疗计划期间使用指定的患者结构作为被辐射掩蔽的区域。 通过一种方法，将患者结构指定为指定的患者结构的上述机会包括向患者提供通过显示器指定患者结构的机会。 可以根据需要包括通过适当使用多叶准直器来实现上述掩蔽。
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公开(公告)号：US11602643B2
公开(公告)日：2023-03-14
申请号：US16237496
申请日：2018-12-31
摘要： A treatment planning apparatus includes: a modeler configured to obtain a model definition, wherein the model definition comprises a first quality metric of a first clinical goal; and a treatment planner having: a model trainer configured to obtain a set of existing treatment plans following desired clinical practice, and to perform model training to obtain a trained model based on the existing treatment plans and the first quality metric of the first clinical goal; an objective generator configured to generate a cost function based on the trained model; and an optimizer configured to determine a treatment plan based on the cost function.
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公开(公告)号：US20210299476A1
公开(公告)日：2021-09-30
申请号：US16836411
申请日：2020-03-31
摘要： A control circuit accesses patient information including anatomical image information of the patient, segmentation information corresponding to the anatomical image information, and a dose map for the radiation treatment plan. The control circuit then generates at least one organ-specific three-dimensional risk map as a function of the patient information and presents that risk map to a user via a display.
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6.发明授权公开(公告)号：US11027147B2
公开(公告)日：2021-06-08
申请号：US16121235
申请日：2018-09-04
发明人： Corey Zankowski , Janne Nord , Maria Isabel Cordero Marcos , Joona Hartman , Jarkko Peltola , Esa Kuusela
IPC分类号： A61N5/10
摘要： A system for estimating a dose from a radiation therapy plan includes a memory that stores machine-readable instructions and a processor communicatively coupled to the memory, the processor operable to execute the instructions to subdivide a representation of a volume of interest into voxels. The processor also determines distances between a planned radiation field origin and each respective voxel. The processor further computes geometry-based expected (GED) metrics based on the distances, a plan parameter, and a field strength parameter. The processor sums the metrics to yield an estimated dose received by the volume of interest from the planned radiation field.
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7.发明授权公开(公告)号：US10315045B2
公开(公告)日：2019-06-11
申请号：US14040095
申请日：2013-09-27
IPC分类号： A61N5/10
摘要： A control circuit provides a user with an opportunity to designate one or more patient structures for a particular patient that are to be protected from radiation. When optimizing a radiation-treatment plan for that patient, then, the control circuit uses the designated patient structure(s) as an area to be masked from radiation during administration of the radiation-treatment plan. By one approach the aforementioned opportunity to designate patient structures as being designated patient structures comprises providing the user with an opportunity to so designate patient structures via a display. The aforementioned masking can be accomplished as desired including by appropriate use of a multi-leaf collimator.
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公开(公告)号：US10159853B2
公开(公告)日：2018-12-25
申请号：US15085804
申请日：2016-03-30
IPC分类号： A61N5/10
摘要： A system for estimating a dose from a proton therapy plan includes a memory that stores machine instructions and a processor coupled to the memory that executes the machine instructions to subdivide a representation of a volume of interest in a patient anatomy traversed by a planned proton field into a plurality of voxels. The processor further executes the machine instructions to determine the distance from the source of the planned proton beam to one of the voxels. The processor also executes the machine instructions to compute the discrete contribution at the voxel to an estimated dose received by the volume of interest from the planned proton beam based on the distance between the source and the volume of interest.
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公开(公告)号：US20150095044A1
公开(公告)日：2015-04-02
申请号：US14040479
申请日：2013-09-27
发明人： Joona Hartman , Maria Isabel Cordero Marcos , Esa Kuusela , Jarkko Yrjana Peltola , Janne Ilmari Nord
IPC分类号： G06F19/00
摘要： Patient data can be used to determine input values to different estimation functions for different treatment types. The estimation functions can each be used to estimate one or more outcome values for the respective treatment. A quality score can be determined using the outcome value(s). A first treatment plan having an optimal quality score can be identified, e.g., by displaying the treatment plans with the quality scores, which may correspond to the outcome values.
摘要翻译： 患者数据可用于确定不同治疗类型的不同估计功能的输入值。 估计函数可以分别用于估计相应治疗的一个或多个结果值。 可以使用结果值确定质量得分。 可以例如通过显示具有与结果值对应的质量得分的治疗计划来确定具有最佳质量得分的第一治疗计划。
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