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公开(公告)号:US11992703B2
公开(公告)日:2024-05-28
申请号:US17323942
申请日:2021-05-18
申请人: Varian Medical Systems International AG. , Varian Medical Systems Particle Therapy GmbH & Co. KG , Varian Medical Systems, Inc.
发明人: Pierre Lansonneur , Perttu Niemela , Viljo Petaja , Simon Busold , Michiko Rossi , Matti Sakari Ropo , Michael Folkerts , Jessica Perez , Christel Smith , Adam Harrington , Eric Abel , Lauri Halko
IPC分类号: A61N5/10
CPC分类号: A61N5/1031 , A61N5/1071 , A61N2005/1074 , A61N2005/1087 , A61N2005/1089
摘要: A method used for planning radiation treatment accessing information that includes calculated doses and calculated dose rates for sub-volumes in a treatment target, and also accessing information that includes values of a measure of the sub-volumes as a function of the calculated doses and the calculated dose rates. A graphical user interface includes a rendering that is based on the calculated doses, the calculated doses rates, and the values of the measure.
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公开(公告)号:US11986677B2
公开(公告)日:2024-05-21
申请号:US17132966
申请日:2020-12-23
发明人: Christel Smith , Corey Zankowski , Jan Hein Timmer , Wolfgang Kaissl , Deepak Khuntia , Eric Abel , Josh Star-Lack , Camille Noel
CPC分类号: A61N5/1069 , A61N5/1049 , A61N5/1067 , A61N5/1077 , A61B2090/0481 , A61N2005/1061 , A61N2005/1094
摘要: In various embodiments, a radiation therapy method can include loading a planning image of a target in a human. In addition, the position of the target can be monitored. A computation can be made of an occurrence of substantial alignment between the position of the target and the target of the planning image. Furthermore, after the computing, a beam of radiation is triggered to deliver a dosage to the target in a short period of time (e.g., less than a second).
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公开(公告)号:US11865361B2
公开(公告)日:2024-01-09
申请号:US16840115
申请日:2020-04-03
申请人: Varian Medical Systems, Inc. , Varian Medical Systems Particle Therapy GmBH , Varian Medical Systems International AG.
发明人: Jessica Perez , Eric Abel , Michael Folkerts , Christel Smith , Adam Harrington , Timo Koponen , Reynald Vanderstraeten , Anthony Magliari , Michiko Rossi
IPC分类号: A61N5/10
CPC分类号: A61N5/1031 , A61N5/10 , A61N5/1007 , A61N2005/1012 , A61N2005/1087
摘要: Embodiments of the present invention provide methods and systems for proton therapy planning that maximize the dose rate for different target sizes for FLASH therapy treatment are disclosed herein according to embodiments of the present invention. According to embodiments, non-standard scanning patterns can be generated, for example, using a TPS optimizer, to maximize dose rate and the overall FLASH effect for specific volumes at risk. The novel scanning patterns can include scanning subfields of a field that are scanned independently or spiral-shaped patterns, for example. In general, spot locations and beam paths between spots are optimized to substantially achieve a desired dose rate in defined regions of the patient's body for FLASH therapy treatment.
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公开(公告)号:US20230191153A1
公开(公告)日:2023-06-22
申请号:US18108539
申请日:2023-02-10
发明人: Viljo PETAJA , Anthony MAGLIARI , Pierre LANSONNEUR , Jessica PEREZ , Michiko ROSSI , Michael FOLKERTS
IPC分类号: A61N5/10
CPC分类号: A61N5/1031 , A61N5/1045 , A61N5/1048 , A61N2005/1074
摘要: Information associated with a radiation treatment plan includes, for example, values of dose per voxel in a target volume, values of dose rate per voxel in the target volume, and values of parameters used when generating the values of dose per voxel and the values of dose rate per voxel. Renderings that include, for example, a rendering of an image of or including the target volume, and a rendering of selected values of the radiation treatment plan, are displayed. When a selection of a region of one of the renderings is received, a displayed characteristic of another one of the renderings is changed based on the selection.
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公开(公告)号:US11673003B2
公开(公告)日:2023-06-13
申请号:US17091445
申请日:2020-11-06
发明人: Reynald Vanderstraeten , Eric Abel , Christel Smith , Anthony Magliari , Timo Koponen , Stanley Mansfield , Charles Adelsheim
CPC分类号: A61N5/1031 , A61N5/1038 , A61N5/1045 , G16H10/60 , G16H20/40 , G16H40/63 , G16H50/50 , A61B6/032 , A61N5/1043 , A61N5/1069 , A61N5/1071
摘要: Radiation treatment planning includes accessing values of parameters such as a number of beams to be directed into sub-volumes in a target, beam directions, and beam energies. Information that specifies limits for the radiation treatment plan are accessed. The limits include a limit on irradiation time for each sub-volume outside the target. Other limits can include a limit on irradiation time for each sub-volume in the target, a limit on dose rate for each sub-volume in the target, and a limit on dose rate for each sub-volume outside the target. The values of the parameters are adjusted until the irradiation time for each sub-volume outside the target satisfies the maximum limit on irradiation time.
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公开(公告)号:US20220370829A1
公开(公告)日:2022-11-24
申请号:US17870286
申请日:2022-07-21
发明人: Santtu Ollila
摘要: A method of determining treatment geometries for a radiotherapy treatment includes providing a patient model having one or more regions of interest (ROIs); defining a delivery coordinate space (DCS); for each beam's eye view (BEV) plane of each vertex in the DCS, and for each ROI, evaluating a dose of the ROI using transport solutions; evaluating a BEV scores of each pixel of the BEV plane using the doses of the one or more ROIs; determining one or more BEV regions in the BEV plane based on the BEV scores; determining a BEV region connectivity manifold based on the BEV regions; determining a set of treatment trajectories based on the BEV region connectivity manifold; and determining one or more IMRT fields. Each treatment trajectory defines a path through a set of vertices in the DCS. Each IMRT field defines a direction of incidence corresponding to a vertex in the DCS.
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公开(公告)号:US11478661B2
公开(公告)日:2022-10-25
申请号:US17036176
申请日:2020-09-29
发明人: Tuomas Tallinen , Daniel Valenzuela , Janne Nord
IPC分类号: A61N5/10
摘要: Systems and methods for radiation treatment planning can include a computing system determining an estimate of a radiation dose distribution within an anatomical region of a patient, and determining a cost matrix representing an objective function, using the estimate of the radiation dose distribution. The computing system can project the cost matrix on each of a plurality of fluence planes. Each of the plurality of fluence planes can be associated with a corresponding gantry-couch orientation of a plurality of gantry-couch orientations of a medical linear accelerator. The computing system can determine, using projections of the cost matrix on each of the plurality of fluence planes, a sequence of gantry-couch orientations among the plurality of gantry-couch orientations representing a treatment path.
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公开(公告)号:US11475991B2
公开(公告)日:2022-10-18
申请号:US16145673
申请日:2018-09-28
发明人: Hannu Laaksonen , Janne Nord , Sami Petri Perttu
摘要: Example methods for adaptive radiotherapy treatment planning using deep learning engines are provided. One example method may comprise obtaining treatment image data associated with a first imaging modality and planning image data associated with a second imaging modality. The treatment image data may be acquired during a treatment phase of a patient. Also, planning image data associated with a second imaging modality may be acquired prior to the treatment phase to generate a treatment plan for the patient. The method may also comprise: in response to determination that an update of the treatment plan is required, processing, using the deep learning engine, the treatment image data and the planning image data to generate output data for updating the treatment plan.
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公开(公告)号:US11406844B2
公开(公告)日:2022-08-09
申请号:US16833801
申请日:2020-03-30
发明人: Xinhui Yang , Armel C. Rosselet , Martin Sabel , Janne I. Nord
摘要: A control circuit accesses topograms of a patient that include patient content that is beyond the portion of the patient that appears in the three-dimensional computed tomography (CT) images for that patient. The control circuit uses those topograms to derive a virtual volumetric structure representing at least some of the patient content that is beyond the aforementioned portion of the patient that appears in the 3D CT images. That virtual volumetric structure can then be used to predict potential collisions when assessing a radiation treatment plan for the patient that utilizes the aforementioned radiation treatment platform. By one approach the topograms include at least two substantially orthographic views of the aforementioned patient content.
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公开(公告)号:US20220219017A1
公开(公告)日:2022-07-14
申请号:US17708423
申请日:2022-03-30
发明人: Reto W. FILIBERTI , Stephen GAUDIO
IPC分类号: A61N5/10
摘要: Systems, devices, and methods for imaging-based calibration of radiation treatment couch position compensations.
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