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公开(公告)号:US20130231370A1
公开(公告)日:2013-09-05
申请号:US13747716
申请日:2013-01-23
IPC分类号: C07D213/76
CPC分类号: C07D213/76 , C07D213/72
摘要: The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
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公开(公告)号:US08865771B2
公开(公告)日:2014-10-21
申请号:US13747716
申请日:2013-01-23
IPC分类号: A01N37/18 , A61K31/165 , A01N43/40 , A61K31/44 , C07C239/00 , C07D213/00 , C07C233/00 , C07C235/00 , C07C237/00 , C07D213/72 , C07D213/76
CPC分类号: C07D213/76 , C07D213/72
摘要: The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
摘要翻译: 本发明涉及可用作电压门控钠通道抑制剂的化合物。 本发明还提供包含本发明化合物的药学上可接受的组合物和使用该组合物治疗各种疾病的方法。
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公开(公告)号:US11203571B2
公开(公告)日:2021-12-21
申请号:US14906089
申请日:2014-07-18
发明人: Sara Sabina Hadida-Ruah , Corey Anderson , Andreas P. Termin , Brian Richard Bear , Vijayalaksmi Arumugam , Paul Krenitsky , James Philip Johnson
IPC分类号: C07C311/46 , A61K31/18
摘要: The invention relates to compounds of formula I or pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels: (I). The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders, including pain.
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