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公开(公告)号：US20170144991A1
公开(公告)日：2017-05-25
申请号：US15126363
申请日：2015-03-19
申请人： Viamet Pharmaceuticals, Inc. , The US, as represented by the Department of Health and Human Services
发明人： William J. Hoekstra , Christopher M. Yates , Mark Behnke , Asaf Alimardanov , Scott A. David , Douglas Franklin Fry
IPC分类号： C07D401/06 , C07D213/38
CPC分类号： C07D401/06 , C07D213/38 , C07D213/84
摘要： The present invention relates to a process for preparing compound 1 that is useful as an antifungal agent. In particular, the invention seeks to provide new methodology for preparing compound 1 and substituted derivatives thereof.
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公开(公告)号：US20170144990A1
公开(公告)日：2017-05-25
申请号：US15126359
申请日：2015-03-19
申请人： Viamet Pharmaceuticals, Inc. , The US, as represented by the Department of Health and Human Services
发明人： William J. Hoekstra , Christopher M. Yates , Mark Behnke , Asaf Alimardanov , Scott A. David , Douglas Franklin Fry
IPC分类号： C07D401/06 , C07D213/56
CPC分类号： C07D401/06 , C07D213/38 , C07D213/50 , C07D213/56 , C07D405/06
摘要： The present invention relates to a process for preparing compound 1 that is useful as an antifungal agent. In particular, the invention seeks to provide new methodology for preparing compound 1 and substituted derivatives thereof.
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公开(公告)号：US20170088540A1
公开(公告)日：2017-03-30
申请号：US15126412
申请日：2015-03-19
申请人： Viamet Pharmaceuticals, Inc. , The US, as represented by the Department of Health and Human Services
发明人： William J. Hoekstra , Christopher M. Yates , Mark Behnke , Asaf Alimardanov , Scott A. David , Douglas Franklin Fry
IPC分类号： C07D401/06 , C07D213/57 , C07F7/18 , C07B57/00
CPC分类号： C07D401/06 , A61K31/4439 , C07B57/00 , C07B2200/07 , C07D213/57 , C07F7/1804
摘要： The present invention relates to a process for preparing compound 1 that is useful as an antifungal agent. In particular, the invention seeks to provide new methodology for preparing compound 1 and substituted derivatives thereof.
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公开(公告)号：US20170088539A1
公开(公告)日：2017-03-30
申请号：US15126402
申请日：2015-03-19
申请人： Viamet Pharmaceuticals, Inc. , The US, as represented by the Department of Health and Human Services
发明人： William J. Hoekstra , Christopher M. Yates , Mark Behnke , Asat Alimardanov , Scott A. David , Douglas Franklin Fry
IPC分类号： C07D401/06 , C07D405/06 , C07D213/38
CPC分类号： C07D401/06 , C07D213/26 , C07D213/38 , C07D405/06
摘要： The present invention relates to a process for preparing compound 1 that is useful as an antifungal agent. In particular, the invention seeks to provide new methodology for preparing compound 1 and substituted derivatives thereof.
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公开(公告)号：US09988365B2
公开(公告)日：2018-06-05
申请号：US15126353
申请日：2015-03-19
发明人： William J. Hoekstra , Nakyen Choy , Carl DeAmicis , Daniel Knueppel , Jim Renga , Michael T. Sullenberger , Gregory Whiteker , Yuanming Zhu , Gary D. Gustafson
IPC分类号： C07D403/06 , C07D401/06 , C07D257/04 , C07D401/14 , C07D213/65 , C07D401/12 , C07D213/50
CPC分类号： C07D401/14 , C07D213/50 , C07D213/65 , C07D401/06 , C07D401/12
摘要： Provided herein are 2-(2,4-difluorophenyl)-1,1-difluoro-1-(5-substituted-pyridin-2-yl)-3-(1H-tetrazol-1-yl)propan-2-ols and 1-(2,4-difluorophenyl)-2,2-difluoro-2-(5-substituted-pyridin-2-yl)ethanones and processes for their preparation.
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公开(公告)号：US09914726B2
公开(公告)日：2018-03-13
申请号：US15126345
申请日：2015-03-19
IPC分类号： C07D401/06 , C07D413/06 , C07D213/127 , A01N43/713
CPC分类号： C07D413/06 , A01N43/713 , C07D213/127 , C07D401/06
摘要： Provided herein are 2-(2,4-difluorophenyl)-1,1-difluoro-1-(5-substituted-pyridin-2-yl)-3-(1H-tetrazol-1-yl)propan-2-ols and processes for their preparation.
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公开(公告)号：US20170158667A1
公开(公告)日：2017-06-08
申请号：US15126353
申请日：2015-03-19
发明人： William J. Hoekstra , Nakyen Choy , Carl DeAmicis , Daniel Knueppel , Jim Renga , Michael T. Sullenberger , Gregory Whiteker , Yuanming Zhu , Gary D. Gustafson
IPC分类号： C07D401/14 , C07D401/06 , C07D213/50 , C07D213/65 , C07D401/12
CPC分类号： C07D401/14 , C07D213/50 , C07D213/65 , C07D401/06 , C07D401/12
摘要： Provided herein are 2-(2,4-difluorophenyl)-1,1-difluoro-1-(5-substituted-pyridin-2-yl)-3-(1H-tetrazol-1-yl)propan-2-ols and 1-(2,4-difluorophenyl)-2,2-difluoro-2-(5-substituted-pyridin-2-yl)ethanones and processes for their preparation.
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公开(公告)号：US20170081316A1
公开(公告)日：2017-03-23
申请号：US15126345
申请日：2015-03-19
IPC分类号： C07D413/06 , A01N43/713
CPC分类号： C07D413/06 , A01N43/713 , C07D213/127 , C07D401/06
摘要： Provided herein are 2-(2,4-difluorophenyl)-1,1-difluoro-1-(5-substituted-pyridin-2-yl)-3-(1H-tetrazol-1-yl)propan-2-ols and processes for their preparation.
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公开(公告)号：US09220265B2
公开(公告)日：2015-12-29
申请号：US14297065
申请日：2014-06-05
发明人： William J. Hoekstra , Christopher M. Yates , Robert J. Schotzinger , Michael R. Loso , Zachary A. Buchan , Michael T. Sullenberger , Gary D. Gustafson
IPC分类号： A01N43/78 , A01N43/713 , C07D401/14 , C07D401/06 , C07D409/14 , C07D417/14 , A01N25/00 , A01N43/647 , A01N43/653
CPC分类号： A01N43/713 , A01N25/00 , A01N43/647 , A01N43/653 , A01N43/78 , C07D401/06 , C07D401/14 , C07D409/14 , C07D417/14
摘要： The instant invention describes compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
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公开(公告)号：US20150024938A1
公开(公告)日：2015-01-22
申请号：US14373304
申请日：2013-01-18
IPC分类号： A01N43/713 , A01N43/653 , A01N57/16 , A01N43/56
CPC分类号： A01N43/713 , A01N43/56 , A01N43/647 , A01N43/653 , A01N57/16
摘要： The present disclosure describes compounds having agricultural fungicidal activity.
摘要翻译： 本公开内容描述了具有农业杀真菌活性的化合物。
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