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1.发明授权公开(公告)号：US09532962B2
公开(公告)日：2017-01-03
申请号：US12740700
申请日：2008-11-03
CPC分类号： A61K31/20 , A61K31/23 , A61K45/06 , A61K2300/00
摘要： Use of medium-chain length fatty acids such as capric acid, caprylic acid or lauric acid and their salts or mono- or di- or triglycerides as nephroprotection agents to protect against renal failure progression in chronic kidney diseases This includes the treatment of kidney diseases associated with nephrectomy, renal fibrosis, glomerular sclerosis and end-stage renal disease Also includes the protection of the kidney against cytotoxic agent used in chemotherapy or autoimmune diseases or transplantation Further includes the treatment of renal failure progression associated with hypertension, infarct, tumor, diabetes mellitus, autoimmunity or inflammation.
摘要翻译： 使用中链长度脂肪酸如癸酸，辛酸或月桂酸及其盐或单 - 或二 - 或甘油三酸酯作为肾保护剂，以防止慢性肾脏疾病中的肾衰竭进展这包括治疗肾脏疾病相关 肾切除术，肾纤维化，肾小球硬化和终末期肾脏疾病还包括对化疗或自身免疫性疾病或移植中使用的细胞毒性剂的肾脏保护进一步包括治疗与高血压，梗塞，肿瘤，糖尿病有关的肾衰竭进展 ，自身免疫或炎症。
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2.发明申请公开(公告)号：US20100286269A1
公开(公告)日：2010-11-11
申请号：US12740700
申请日：2008-11-03
CPC分类号： A61K31/20 , A61K31/23 , A61K45/06 , A61K2300/00
摘要： Use of medium-chain length fatty acids such as capric acid, caprylic acid or lauric acid and their salts or mono- or di- or triglycerides as nephroprotection agents to protect against renal failure progression in chronic kidney diseases This includes the treatment of kidney diseases associated with nephrectomy, renal fibrosis, glomerular scelrosis and end-stage renal disease Also includes the protection of the kidney against cytotoxic agent used in chemotherapy or autoimmune diseases or transplantation Further includes the treatment of renal failure progression associated with hypertension, infarct, tumour, diabetes mellitus, autoimmunity or inflammation.
摘要翻译： 使用中链长度脂肪酸如癸酸，辛酸或月桂酸及其盐或单 - 或二 - 或甘油三酸酯作为肾保护剂，以防止慢性肾脏疾病中的肾衰竭进展这包括治疗肾脏疾病相关 肾切除术，肾纤维化，肾小球结肠炎和终末期肾脏疾病还包括对化疗或自身免疫性疾病或移植中使用的细胞毒性剂的肾脏保护进一步包括治疗与高血压，梗塞，肿瘤，糖尿病相关的肾衰竭进展 ，自身免疫或炎症。
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