专利检索 ap:("Vincent SANDANAYAKA" OR "Jasbir SINGH" OR "Li-Ming ZHOU" OR "Mark E. GURNEY") AND inv:"Li-Ming ZHOU" 第 1 页

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发明申请
BIARYL NITROGEN-HETEROCYCLE INHIBITORS OF LTA4H FOR TREATING INFLAMMATION 失效
标题翻译： LTA4H用于治疗炎症的BIARYL NITROGEN-HETEROCYCLE INHIBITORS

公开(公告)号：US20070149544A1

公开(公告)日：2007-06-28

申请号：US11462278

申请日：2006-08-03

申请人： Vincent SANDANAYAKA , Jasbir SINGH , Li-Ming ZHOU , Mark E. GURNEY

发明人： Vincent SANDANAYAKA , Jasbir SINGH , Li-Ming ZHOU , Mark E. GURNEY

IPC分类号： A61K31/495 , A61K31/445 , C07D211/56 , C07D241/04

CPC分类号： C07D295/033 , C07D211/58 , C07D295/096 , C07D295/15 , C07D333/16 , C07D333/28

摘要： The present invention relates to a chemical genus of biaryl nitrogen-attached heterocycles that are inhibitors of LTA4H (leukotriene A4 hydrolase). The compounds have the general formula They are useful for the treatment and prevention and prophylaxis of inflammatory diseases and disorders.

摘要翻译： 本发明涉及作为LTA4H（白三烯A4水解酶）抑制剂的联芳基氮连接杂环化学属。这些化合物具有通式，它们可用于治疗和预防和预防炎性疾病和病症。