公开(公告)号：US10238447B2

公开(公告)日：2019-03-26

申请号：US14940863

申请日：2015-11-13

Applicant: Virginia Tech Intellectual Properties, Inc.

Inventor： Robert Neal, II ,  Rafael V Davalos

IPC: A61B18/12 ,  A61B18/18 ,  A61B34/10 ,  C12N13/00 ,  A61B18/14 ,  A61B18/00

Abstract: A medical system for ablating a tissue site with real-time monitoring during an electroporation treatment procedure. A pulse generator generates a pre-treatment (PT) test signal having a frequency of at least 1 MHz prior to the treatment procedure and intra-treatment (IT) test signals during the treatment procedure. A treatment control module determines impedance values from the PT test signal and IT test signals and determines a progress of electroporation and an end point of treatment in real-time based on the determined impedance values while the treatment progresses.