公开(公告)号：US20210361341A1

公开(公告)日：2021-11-25

申请号：US17338960

申请日：2021-06-04

Applicant: Virginia Tech Intellectual Properties Inc. ,  AngioDynamics, Inc.

Inventor： Robert Neal, II ,  Rafael V. Davalos

IPC: A61B18/12 ,  A61B18/14 ,  C12N13/00 ,  A61B18/18 ,  A61B34/10

Abstract: A medical system for ablating a tissue site with real-time monitoring during an electroporation treatment procedure. A pulse generator generates a pre-treatment (PT) test signal prior to the treatment procedure and intra-treatment (IT) test signals during the treatment procedure. A treatment control module determines impedance values from the PT test signal and IT test signals and determines a progress of electroporation and an end point of treatment in real-time based on the determined impedance values while the treatment progresses.

公开(公告)号：US20190175248A1

公开(公告)日：2019-06-13

申请号：US16280511

申请日：2019-02-20

Applicant: Virginia Tech Intellectual Properties Inc.

Inventor： Robert Neal, II ,  Rafael V. Davalos

IPC: A61B18/12 ,  A61B34/10 ,  A61B18/14 ,  C12N13/00 ,  A61B18/18

Abstract: A medical system for ablating a tissue site with real-time monitoring during an electroporation treatment procedure. A pulse generator generates a pre-treatment (PT) test signal prior to the treatment procedure and intra-treatment (IT) test signals during the treatment procedure. A treatment control module determines impedance values from the PT test signal and IT test signals and determines a progress of electroporation and an end point of treatment in real-time based on the determined impedance values while the treatment progresses.

公开(公告)号：US11890046B2

公开(公告)日：2024-02-06

申请号：US17338960

申请日：2021-06-04

Applicant: Virginia Tech Intellectual Properties Inc. ,  AngioDynamics, Inc.

Inventor： Robert Neal, II ,  Rafael V. Davalos

IPC: A61B18/12 ,  A61B18/14 ,  C12N13/00 ,  A61B18/18 ,  A61B34/10 ,  A61B18/00

CPC classification number: A61B18/1206 ,  A61B18/14 ,  A61B18/1477 ,  A61B18/18 ,  A61B34/10 ,  C12N13/00 ,  A61B2018/0016 ,  A61B2018/00577 ,  A61B2018/00613 ,  A61B2018/00666 ,  A61B2018/00672 ,  A61B2018/00678 ,  A61B2018/00767 ,  A61B2018/00875 ,  A61B2018/1425 ,  A61B2034/104

Abstract: A medical system for ablating a tissue site with real-time monitoring during an electroporation treatment procedure. A pulse generator generates a pre-treatment (PT) test signal prior to the treatment procedure and intra-treatment (IT) test signals during the treatment procedure. A treatment control module determines impedance values from the PT test signal and IT test signals and determines a progress of electroporation and an end point of treatment in real-time based on the determined impedance values while the treatment progresses.

公开(公告)号：US20240173063A1

公开(公告)日：2024-05-30

申请号：US18528051

申请日：2023-12-04

Applicant: Virginia Tech Intellectual Properties Inc. ,  AngioDynamics, Inc.

Inventor： Robert Neal, II ,  Rafael V. Davalos

IPC: A61B18/12 ,  A61B18/00 ,  A61B18/14 ,  A61B18/18 ,  A61B34/10 ,  C12N13/00

CPC classification number: A61B18/1206 ,  A61B18/14 ,  A61B18/1477 ,  A61B18/18 ,  A61B34/10 ,  C12N13/00 ,  A61B2018/0016 ,  A61B2018/00577 ,  A61B2018/00613 ,  A61B2018/00666 ,  A61B2018/00672 ,  A61B2018/00678 ,  A61B2018/00767 ,  A61B2018/00875 ,  A61B2018/1425 ,  A61B2034/104

Abstract: A medical system for ablating a tissue site with real-time monitoring during an electroporation treatment procedure. A pulse generator generates a pre-treatment (PT) test signal prior to the treatment procedure and intra-treatment (IT) test signals during the treatment procedure. A treatment control module determines impedance values from the PT test signal and IT test signals and determines a progress of electroporation and an end point of treatment in real-time based on the determined impedance values while the treatment progresses.

公开(公告)号：US10238447B2

公开(公告)日：2019-03-26

申请号：US14940863

申请日：2015-11-13

Applicant: Virginia Tech Intellectual Properties, Inc.

Inventor： Robert Neal, II ,  Rafael V Davalos

IPC: A61B18/12 ,  A61B18/18 ,  A61B34/10 ,  C12N13/00 ,  A61B18/14 ,  A61B18/00

Abstract: A medical system for ablating a tissue site with real-time monitoring during an electroporation treatment procedure. A pulse generator generates a pre-treatment (PT) test signal having a frequency of at least 1 MHz prior to the treatment procedure and intra-treatment (IT) test signals during the treatment procedure. A treatment control module determines impedance values from the PT test signal and IT test signals and determines a progress of electroporation and an end point of treatment in real-time based on the determined impedance values while the treatment progresses.