-
1.发明申请Compositions, Methods, and Kits for Selective Amplification of Nucleic Acids 审中-公开用于核酸选择性扩增的组合物，方法和试剂盒公开(公告)号：US20100184159A1
公开(公告)日：2010-07-22
申请号：US12692557
申请日：2010-01-22
IPC分类号： C12P19/34
CPC分类号： C12Q1/6827 , C12Q1/6844 , C12Q1/6853 , Y02A50/54 , C12Q2525/307 , C12Q2531/125 , C12Q2525/117 , C12Q2561/125 , C12Q2537/143
摘要： The current teachings are directed to compositions, methods, and kits for selectively amplifying and for detecting target sequences. In some embodiments, a circularizable probe and/or a probe pair are disclosed for selectively amplifying target sequences. Methods for selectively amplifying target sequences are also disclosed, as are methods for detecting selectively amplified target sequences. Certain embodiments of the disclosed methods comprise a circularizable probe, a probe pair, comprising a first probe and a second probe, or both. In certain embodiments, a multiplicity of different circularizable probes, a multiplicity of different probe sets, or a multiplicity of different circularizable probes and a multiplicity of different probe sets are provided to selectively amplify or to detect a multiplicity of different target sequences, typically in a multiplex reaction. According to certain disclosed methods, surrogates of the target sequences are selectively amplified, including without limitation ligated probes, first amplification products, second amplification products, or combinations thereof. In some embodiments, selectively amplified target sequences or their surrogates are detected, directly or indirectly, indicating the presence of the corresponding target sequence. Kits to facilitate the performance of the disclosed methods are also provided.
摘要翻译： 目前的教导涉及用于选择性扩增和检测靶序列的组合物，方法和试剂盒。 在一些实施方案中，公开了可圆化探针和/或探针对，用于选择性扩增靶序列。 还公开了选择性扩增靶序列的方法，以及用于检测选择性扩增的靶序列的方法。 所公开方法的某些实施方案包括可圆化的探针，包括第一探针和第二探针的探针对，或两者。 在某些实施方案中，提供多个不同的可圆化探针，多个不同的探针组或多个不同的可环化探针和多个不同的探针组，以选择性地扩增或检测多种不同靶序列，通常在 多重反应。 根据某些公开的方法，选择性扩增靶序列的替代物，包括但不限于连接的探针，第一扩增产物，第二扩增产物或其组合。 在一些实施方案中，直接或间接检测选择性扩增的靶序列或其替代物，表明存在相应的靶序列。 还提供了用于促进所公开方法的性能的套件。
-
2.发明申请Compositions, methods, and kits for selective amplification of nucleic acids 审中-公开用于选择性扩增核酸的组合物，方法和试剂盒公开(公告)号：US20070212695A1
公开(公告)日：2007-09-13
申请号：US11331599
申请日：2006-01-12
CPC分类号： C12Q1/6827 , C12Q1/6844 , C12Q1/6853 , Y02A50/54 , C12Q2525/307 , C12Q2531/125 , C12Q2525/117 , C12Q2561/125 , C12Q2537/143
摘要： The current teachings are directed to compositions, methods, and kits for selectively amplifying and for detecting target sequences. In some embodiments, a circularizable probe and/or a probe pair are disclosed for selectively amplifying target sequences. Methods for selectively amplifying target sequences are also disclosed, as are methods for detecting selectively amplified target sequences. Certain embodiments of the disclosed methods comprise a circularizable probe, a probe pair, comprising a first probe and a second probe, or both. In certain embodiments, a multiplicity of different circularizable probes, a multiplicity of different probe sets, or a multiplicity of different circularizable probes and a multiplicity of different probe sets are provided to selectively amplify or to detect a multiplicity of different target sequences, typically in a multiplex reaction. According to certain disclosed methods, surrogates of the target sequences are selectively amplified, including without limitation ligated probes, first amplification products, second amplification products, or combinations thereof. In some embodiments, selectively amplified target sequences or their surrogates are detected, directly or indirectly, indicating the presence of the corresponding target sequence. Kits to facilitate the performance of the disclosed methods are also provided.
摘要翻译： 目前的教导涉及用于选择性扩增和检测靶序列的组合物，方法和试剂盒。 在一些实施方案中，公开了可圆化探针和/或探针对，用于选择性扩增靶序列。 还公开了选择性扩增靶序列的方法，以及用于检测选择性扩增的靶序列的方法。 所公开方法的某些实施方案包括可圆化的探针，包括第一探针和第二探针的探针对，或两者。 在某些实施方案中，提供多个不同的可圆化探针，多个不同的探针组或多个不同的可环化探针和多个不同的探针组，以选择性地扩增或检测多种不同靶序列，通常在 多重反应。 根据某些公开的方法，选择性扩增靶序列的替代物，包括但不限于连接的探针，第一扩增产物，第二扩增产物或其组合。 在一些实施方案中，直接或间接检测选择性扩增的靶序列或其替代物，表明存在相应的靶序列。 还提供了用于促进所公开方法的性能的套件。
-
公开(公告)号：US20050195555A1
公开(公告)日：2005-09-08
申请号：US10792257
申请日：2004-03-02
申请人： Aaron Steyskal , Larry Mosley , Tony Tran
发明人： Aaron Steyskal , Larry Mosley , Tony Tran
IPC分类号： H01G4/228
摘要： A capacitor with reduced equivalent series resistance and reduces equivalent series inductance is provided. Capacitors are provided with multiple plate assemblies that couple to a common single first polarity terminal. Capacitors are also provided with multiple plate assemblies that each couple to a respective second polarity terminal. Fan-like plate assemblies are arranged to provide increased capacitance with reduced equivalent series resistance and reduces equivalent series inductance. Capacitors are provided that mount using surface mounting technology. Capacitors are provided that conform to existing capacitor form factors.
摘要翻译： 提供了具有降低的等效串联电阻并减小等效串联电感的电容器。 电容器具有多个板组件，其耦合到公共单个第一极性端子。 电容器还设置有多个板组件，每个板组件耦合到相应的第二极性端子。 风扇板组件布置成提供增加的电容，减少等效串联电阻并减小等效的串联电感。 提供使用表面贴装技术安装的电容器。 提供符合现有电容器形状因素的电容器。
-
-
搜索结果
3 条记录 (耗时 0.017 秒)
