Fluidics platform and method for sample preparation and analysis
    1.
    发明授权
    Fluidics platform and method for sample preparation and analysis 有权
    流体平台和样品制备和分析方法

    公开(公告)号:US08808643B1

    公开(公告)日:2014-08-19

    申请号:US13228391

    申请日:2011-09-08

    IPC分类号: B01L3/02

    摘要: Herein provided are fluidics platform and method for sample preparation and analysis. The fluidics platform is capable of analyzing DNA from blood samples using amplification assays such as polymerase-chain-reaction assays and loop-mediated-isothermal-amplification assays. The fluidics platform can also be used for other types of assays and analyzes. In some embodiments, a sample in a sealed tube can be inserted directly. The following isolation, detection, and analyzes can be performed without a user's intervention. The disclosed platform may also comprises a sample preparation system with a magnetic actuator, a heater, and an air-drying mechanism, and fluid manipulation processes for extraction, washing, elution, assay assembly, assay detection, and cleaning after reactions and between samples.

    摘要翻译: 本文提供了流动平台和样品制备和分析方法。 流体学平台能够使用诸如聚合酶链反应测定和环介导等温扩增测定之类的扩增测定法从血液样品中分析DNA。 流体学平台也可用于其他类型的测定和分析。 在一些实施例中,密封管中的样品可以直接插入。 无需用户干预即可执行以下隔离,检测和分析。 所公开的平台还可以包括具有磁性致动器,加热器和空气干燥机构的样品制备系统,以及用于在反应之后和样品之间的萃取,洗涤,洗脱,测定组装,测定检测和清洁的流体操纵过程。