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    Guidewire with an intermediate variable stiffness section
    1.
    发明授权
    Guidewire with an intermediate variable stiffness section 有权
    导丝具有中间可变刚度部分

    公开(公告)号：US06524301B1

    公开(公告)日：2003-02-25

    申请号：US09748294

    申请日：2000-12-21

    申请人： W. Stan Wilson ,  Robert C. Esselstein ,  Wayne E. Cornish ,  Mark T. Richardson

    发明人： W. Stan Wilson ,  Robert C. Esselstein ,  Wayne E. Cornish ,  Mark T. Richardson

    IPC分类号： A61M2500

    CPC分类号： A61M25/09 ,  A61M2025/09083 ,  A61M2025/09133

    摘要： The invention is directed to an guide wire for intraluminal deployment of a medical device within a patient, the guide wire having an elongate core member with an intermediate core section comprising a plurality of contiguous segments in alignment with the longitudinal axis of the core member with alternating flexible and rigid core segments, so that the articulated section bends in a discontinuous, discrete manner when advanced through a curved blood vessel or other body lumen within the patient. When an obstruction on a vessel wall causes the catheter or other coaxial device to be impeded, the guide wire and intermediate core section may alternately be advanced and retracted a short distance through the catheter distal tip causing a “nodding” motion of the catheter tip while the catheter is pushed through the vessel, so as to avoid and bypass the vessel obstruction.

    摘要翻译： 本发明涉及一种用于在患者体内腔内部署医疗装置的导丝，所述导丝具有细长的芯部件，所述细长的芯部件具有中间的芯部分，所述中间纤芯部分包括与所述芯部件的纵向轴线对准的多个连续部分， 柔性和刚性的芯段，使得铰接部分在通过患者体内的弯曲血管或其他体腔前进时以不连续的离散方式弯曲。 当血管壁上的阻塞物导致导管或其它同轴装置被阻碍时，引导线和中间芯部分可以交替地前进并缩回穿过导管远端的短距离，导致导管末端的“点头”运动，同时 导管被推过血管，以避免和绕过血管阻塞。

    Guidewire with an intermediate variable stiffness section
    2.
    发明授权
    Guidewire with an intermediate variable stiffness section 有权

    公开(公告)号：US06638266B2

    公开(公告)日：2003-10-28

    申请号：US10310392

    申请日：2002-12-05

    申请人： W. Stan Wilson ,  Robert C. Esselstein ,  Wayne E. Cornish ,  Mark T. Richardson

    发明人： W. Stan Wilson ,  Robert C. Esselstein ,  Wayne E. Cornish ,  Mark T. Richardson

    IPC分类号： A61M2500

    CPC分类号： A61M25/09 ,  A61M2025/09083 ,  A61M2025/09133

    摘要： The invention is directed to an guide wire for intraluminal deployment of a medical device within a patient, the guide wire having an elongate core member with an intermediate core section comprising a plurality of contiguous segments in alignment with the longitudinal axis of the core member with alternating flexible and rigid core segments, so that the articulated section bends in a discontinuous, discrete manner when advanced through a curved blood vessel or other body lumen within the patient. When an obstruction on a vessel wall causes the catheter or other coaxial device to be impeded, the guide wire and intermediate core section may alternately be advanced and retracted a short distance through the catheter distal tip causing a “nodding” motion of the catheter tip while the catheter is pushed through the vessel, so as to avoid and bypass the vessel obstruction.

    Composite guidewire withdrawn and filled tube construction
    7.
    发明授权
    Composite guidewire withdrawn and filled tube construction 有权
    复合导丝取出并填充管结构

    公开(公告)号：US08226577B2

    公开(公告)日：2012-07-24

    申请号：US12554178

    申请日：2009-09-04

    申请人： Marc M. Jalisi ,  David M. Anderson ,  Wayne E. Cornish ,  Nancy A. Nicotra ,  Mark T. Richardson

    发明人： Marc M. Jalisi ,  David M. Anderson ,  Wayne E. Cornish ,  Nancy A. Nicotra ,  Mark T. Richardson

    IPC分类号： A61B5/00

    CPC分类号： A61M25/09 ,  A61M2025/09175

    摘要： The present invention is directed to an intracorporeal device, preferably a guidewire, and method for making the device. The guidewire of the present invention is formed, at least in part, of a composite elongate core formed, at least in part, of precipitation hardened material. The elongate core members of the present invention will have an ultimate tensile strength and modulus of elasticity greater than the same for an identically dimensioned elongate member formed from superelastic NITINOL alone.

    摘要翻译： 本发明涉及体内装置，优选导丝，以及制造该装置的方法。 本发明的导丝至少部分地形成有至少部分由沉淀硬化材料形成的复合细长芯。 对于由超弹性NITINOL单独形成的相同尺寸的细长构件，本发明的细长芯构件将具有大于相同尺寸的极限拉伸强度和弹性模量。

    Composite guide wire with drawn and filled tube construction
    8.
    发明授权
    Composite guide wire with drawn and filled tube construction 有权
    复合导丝带拉丝和填充管结构

    公开(公告)号：US08123702B2

    公开(公告)日：2012-02-28

    申请号：US12046183

    申请日：2008-03-11

    申请人： Ryan Grandfield ,  Mark T. Richardson ,  Peter D'Aquanni ,  Wayne E. Cornish ,  Jonathan M. Howland

    发明人： Ryan Grandfield ,  Mark T. Richardson ,  Peter D'Aquanni ,  Wayne E. Cornish ,  Jonathan M. Howland

    IPC分类号： A61B5/00

    CPC分类号： A61M25/09 ,  A61M2025/09175

    摘要： The present invention is directed to an intracorporeal device, preferably a guidewire, and method for making the device. The guidewire of the present invention is formed, at least in part, of a composite elongate core formed, at least in part, of precipitation hardened material. The elongate core members of the present invention will have an ultimate tensile strength and modulus of elasticity greater than the same for an identically dimensioned elongate member formed from superelastic NITINOL alone.

    摘要翻译： 本发明涉及体内装置，优选导丝，以及制造该装置的方法。 本发明的导丝至少部分地形成有至少部分由沉淀硬化材料形成的复合细长芯。 对于由超弹性NITINOL单独形成的相同尺寸的细长构件，本发明的细长芯构件将具有大于相同尺寸的极限拉伸强度和弹性模量。

    GUIDEWIRE HAVING LINEAR CHANGE IN STIFFNESS
    9.
    发明申请
    GUIDEWIRE HAVING LINEAR CHANGE IN STIFFNESS 有权
    具有线性变化的GUIDEWIRE

    公开(公告)号：US20090062773A1

    公开(公告)日：2009-03-05

    申请号：US12047008

    申请日：2008-03-12

    申请人： Wayne E. Cornish ,  John Schreiner ,  James Jacobs ,  Marc M. Jalisi ,  Mark T. Richardson ,  Kent C. Stalker ,  Olin J. Palmer

    发明人： Wayne E. Cornish ,  John Schreiner ,  James Jacobs ,  Marc M. Jalisi ,  Mark T. Richardson ,  Kent C. Stalker ,  Olin J. Palmer

    IPC分类号： A61M25/09

    CPC分类号： A61B5/6851 ,  A61M25/09 ,  A61M2025/09083 ,  A61M2025/09175

    摘要： The invention is directed to a guidewire having a distal section with multiple distally tapered core segments with at least two contiguous distally tapering core segments in which the most distal tapered core segment preferably has a greater degree of taper than the proximally contiguous tapered core segment. The invention is also directed to an elongated intracorporeal device, preferably a guidewire or section thereof, that has a core member or the like with a plurality of contiguous tapered segments having taper angles that are configured to produce a linear change in stiffness over a longitudinal section of the device. The device may also have a core section with a continuously changing taper angle to produce a curvilinear profile that preferably is configured to produce a linear change in stiffness of the core over a longitudinal section of the device.

    摘要翻译： 本发明涉及一种具有多个具有至少两个相邻的远端锥形芯段的多个远端锥形芯部段的远端部分，其中最远端锥形芯部段优选地具有比近端相邻的锥形芯部分更大的锥度。 本发明还涉及一种细长的体内装置，优选的导丝或其一部分，其具有芯构件或类似物，多个相邻的锥形段具有锥形角，该锥形角构造成在纵向截面上产生刚度的线性变化 的设备。 该装置还可以具有连续变化的锥角的芯部分，以产生曲线轮廓，该曲线轮廓优选地被配置为在装置的纵向部分上产生芯的刚度的线性变化。

    Guidewire having linear change in stiffness
    10.
    发明授权
    Guidewire having linear change in stiffness 有权
    导丝具有刚度线性变化

    公开(公告)号：US08308660B2

    公开(公告)日：2012-11-13

    申请号：US13150973

    申请日：2011-06-01

    申请人： Wayne E. Cornish ,  John F. Schreiner ,  James M. Jacobs ,  Marc M. Jalisi ,  Mark T. Richardson ,  Kent C. B. Stalker ,  Olin J. Palmer

    发明人： Wayne E. Cornish ,  John F. Schreiner ,  James M. Jacobs ,  Marc M. Jalisi ,  Mark T. Richardson ,  Kent C. B. Stalker ,  Olin J. Palmer

    IPC分类号： A61B5/00

    CPC分类号： A61B5/6851 ,  A61M25/09 ,  A61M2025/09083 ,  A61M2025/09175

    摘要： The invention is directed to a guidewire having a distal section with multiple distally tapered core segments with at least two contiguous distally tapering core segments in which the most distal tapered core segment preferably has a greater degree of taper than the proximally contiguous tapered core segment. The invention is also directed to an elongated intracorporeal device, preferably a guidewire or section thereof, that has a core member or the like with a plurality of contiguous tapered segments having taper angles that are configured to produce a linear change in stiffness over a longitudinal section of the device. The device may also have a core section with a continuously changing taper angle to produce a curvilinear profile that preferably is configured to produce a linear change in stiffness of the core over a longitudinal section of the device.

    摘要翻译： 本发明涉及一种具有多个具有至少两个相邻的远端锥形芯段的多个远端锥形芯部段的远端部分，其中最远端锥形芯部段优选地具有比近端相邻的锥形芯部分更大的锥度。 本发明还涉及一种细长的体内装置，优选的导丝或其一部分，其具有芯构件或类似物，多个相邻的锥形段具有锥形角，该锥形角构造成在纵向截面上产生刚度线性变化 的设备。 该装置还可以具有连续变化的锥角的芯部分，以产生曲线轮廓，该曲线轮廓优选地被配置为在装置的纵向部分上产生芯的刚度的线性变化。