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    Guidewire having linear change in stiffness
    1.
    发明授权
    Guidewire having linear change in stiffness 有权
    导丝具有刚度线性变化

    公开(公告)号：US08308660B2

    公开(公告)日：2012-11-13

    申请号：US13150973

    申请日：2011-06-01

    申请人： Wayne E. Cornish ,  John F. Schreiner ,  James M. Jacobs ,  Marc M. Jalisi ,  Mark T. Richardson ,  Kent C. B. Stalker ,  Olin J. Palmer

    发明人： Wayne E. Cornish ,  John F. Schreiner ,  James M. Jacobs ,  Marc M. Jalisi ,  Mark T. Richardson ,  Kent C. B. Stalker ,  Olin J. Palmer

    IPC分类号： A61B5/00

    CPC分类号： A61B5/6851 ,  A61M25/09 ,  A61M2025/09083 ,  A61M2025/09175

    摘要： The invention is directed to a guidewire having a distal section with multiple distally tapered core segments with at least two contiguous distally tapering core segments in which the most distal tapered core segment preferably has a greater degree of taper than the proximally contiguous tapered core segment. The invention is also directed to an elongated intracorporeal device, preferably a guidewire or section thereof, that has a core member or the like with a plurality of contiguous tapered segments having taper angles that are configured to produce a linear change in stiffness over a longitudinal section of the device. The device may also have a core section with a continuously changing taper angle to produce a curvilinear profile that preferably is configured to produce a linear change in stiffness of the core over a longitudinal section of the device.

    摘要翻译： 本发明涉及一种具有多个具有至少两个相邻的远端锥形芯段的多个远端锥形芯部段的远端部分，其中最远端锥形芯部段优选地具有比近端相邻的锥形芯部分更大的锥度。 本发明还涉及一种细长的体内装置，优选的导丝或其一部分，其具有芯构件或类似物，多个相邻的锥形段具有锥形角，该锥形角构造成在纵向截面上产生刚度线性变化 的设备。 该装置还可以具有连续变化的锥角的芯部分，以产生曲线轮廓，该曲线轮廓优选地被配置为在装置的纵向部分上产生芯的刚度的线性变化。

    Guidewire having linear change in stiffness
    2.
    发明授权
    Guidewire having linear change in stiffness 有权
    导丝具有刚度线性变化

    公开(公告)号：US07972283B2

    公开(公告)日：2011-07-05

    申请号：US12047008

    申请日：2008-03-12

    申请人： Wayne E. Cornish ,  John F. Schreiner ,  James M. Jacobs ,  Marc M. Jalisi ,  Mark T. Richardson ,  Kent C. B. Stalker ,  Olin J. Palmer

    发明人： Wayne E. Cornish ,  John F. Schreiner ,  James M. Jacobs ,  Marc M. Jalisi ,  Mark T. Richardson ,  Kent C. B. Stalker ,  Olin J. Palmer

    IPC分类号： A61B5/00

    CPC分类号： A61B5/6851 ,  A61M25/09 ,  A61M2025/09083 ,  A61M2025/09175

    摘要： The invention is directed to a guidewire having a distal section with multiple distally tapered core segments with at least two contiguous distally tapering core segments in which the most distal tapered core segment preferably has a greater degree of taper than the proximally contiguous tapered core segment. The invention is also directed to an elongated intracorporeal device, preferably a guidewire or section thereof, that has a core member or the like with a plurality of contiguous tapered segments having taper angles that are configured to produce a linear change in stiffness over a longitudinal section of the device. The device may also have a core section with a continuously changing taper angle to produce a curvilinear profile that preferably is configured to produce a linear change in stiffness of the core over a longitudinal section of the device.

    摘要翻译： 本发明涉及一种具有多个具有至少两个相邻的远端锥形芯段的多个远端锥形芯部段的远端部分，其中最远端锥形芯部段优选地具有比近端相邻的锥形芯部分更大的锥度。 本发明还涉及一种细长的体内装置，优选的导丝或其一部分，其具有芯构件或类似物，多个相邻的锥形段具有锥形角，该锥形角构造成在纵向截面上产生刚度线性变化 的设备。 该装置还可以具有连续变化的锥角的芯部分，以产生曲线轮廓，该轮廓优选被配置成在装置的纵向部分上产生芯的刚度的线性变化。

    Cardiac lead having implantable stiffening structures for fixation
    3.
    发明授权
    Cardiac lead having implantable stiffening structures for fixation 有权
    心脏导联具有可植入的硬化结构用于固定

    公开(公告)号：US08442656B2

    公开(公告)日：2013-05-14

    申请号：US11422014

    申请日：2006-06-02

    申请人： Bruce A. Tockman ,  Brian D. Soltis ,  Eric T. Johnson ,  Kent C. B. Stalker ,  Peter J. D'aquanni ,  Paul E. Zarembo

    发明人： Bruce A. Tockman ,  Brian D. Soltis ,  Eric T. Johnson ,  Kent C. B. Stalker ,  Peter J. D'aquanni ,  Paul E. Zarembo

    IPC分类号： A61N1/05

    CPC分类号： A61N1/056 ,  A61N1/0573 ,  A61N2001/0585

    摘要： A cardiac lead adapted for fixation at least partially within a cardiac vessel. The lead includes, in one embodiment, an elongate lead body defining a proximal region and a distal region including a distal end region having at least one electrode and a distal tip. The distal end region is configured such that the electrode and the distal tip can be implanted in the cardiac vessel. Stiffening structures in the distal region of the lead are adapted to stiffen selected portions of the lead for fixation of the electrode within the cardiac vessel. In some embodiments, the stiffening structures include an implantable member adapted to be implanted in a lumen of the lead. In other embodiments, the stiffening structures include a sheath adapted to be deployed over the lead body. In still other embodiments, the stiffening structures are integral to the lead and/or the lead body.

    摘要翻译： 适于至少部分地固定在心脏血管内的心脏引线。 在一个实施例中，引线包括限定近端区域的细长引线体和包括具有至少一个电极和远端尖端的远端区域的远侧区域。 远端区域被构造成使得电极和远端尖端可以植入心脏血管。 铅的远端区域中的加强结构适于加强导线的选定部分，以将电极固定在心脏血管内。 在一些实施例中，加强结构包括适于植入在引导管腔中的可植入部件。 在其他实施例中，加强结构包括适于部署在引线主体上的护套。 在其他实施例中，加强结构与引线和/或引线主体成一体。

    CARDIAC LEAD HAVING STIFFENING STRUCTURES FOR FIXATION
    4.
    发明申请
    CARDIAC LEAD HAVING STIFFENING STRUCTURES FOR FIXATION 审中-公开
    具有固定结构的CARDIAC引线

    公开(公告)号：US20070282413A1

    公开(公告)日：2007-12-06

    申请号：US11422012

    申请日：2006-06-02

    申请人： Bruce A. Tockman ,  Brian D. Soltis ,  Eric T. Johnson ,  Kent C. B. Stalker ,  Peter J. D' aquanni ,  Paul E. Zarembo

    发明人： Bruce A. Tockman ,  Brian D. Soltis ,  Eric T. Johnson ,  Kent C. B. Stalker ,  Peter J. D' aquanni ,  Paul E. Zarembo

    IPC分类号： A61N1/05

    CPC分类号： A61N1/057 ,  A61N2001/0585

    摘要： A cardiac lead adapted for fixation at least partially within a cardiac vessel. The lead includes, in one embodiment, an elongate lead body defining a proximal region and a distal region including a distal end region having at least one electrode and a distal tip. The distal end region is configured such that the electrode and the distal tip can be implanted in the cardiac vessel. Stiffening structures in the distal region of the lead are adapted to stiffen selected portions of the lead for fixation of the electrode within the cardiac vessel. In some embodiments, the stiffening structures include an implantable member adapted to be implanted in a lumen of the lead. In other embodiments, the stiffening structures include a sheath adapted to be deployed over the lead body. In still other embodiments, the stiffening structures are integral to the lead and/or the lead body.

    摘要翻译： 适于至少部分地固定在心脏血管内的心脏引线。 在一个实施例中，引线包括限定近端区域的细长引线体和包括具有至少一个电极和远端尖端的远端区域的远侧区域。 远端区域被构造成使得电极和远端尖端可以植入心脏血管。 铅的远端区域中的加强结构适于加强导线的选定部分，以将电极固定在心脏血管内。 在一些实施例中，加强结构包括适于植入在引导管腔中的可植入部件。 在其他实施例中，加强结构包括适于部署在引线主体上的护套。 在其他实施例中，加强结构与引线和/或引线主体成一体。

    Embolic filtering devices
    5.
    发明授权
    Embolic filtering devices 有权
    栓塞过滤装置

    公开(公告)号：US07252675B2

    公开(公告)日：2007-08-07

    申请号：US10260710

    申请日：2002-09-30

    申请人： Andy E. Denison ,  William J. Harrison ,  Benjamin C. Huter ,  Scott J. Huter ,  John E. Papp ,  Steven T. Saville ,  Kent C. B. Stalker

    发明人： Andy E. Denison ,  William J. Harrison ,  Benjamin C. Huter ,  Scott J. Huter ,  John E. Papp ,  Steven T. Saville ,  Kent C. B. Stalker

    IPC分类号： A61M29/00

    CPC分类号： A61F2/013 ,  A61F2002/015 ,  A61F2002/018 ,  A61F2230/0006 ,  A61F2230/008

    摘要： An expandable frame for an embolic filtering device used to capture embolic debris in a body vessel includes a first half frame having a first control arm connected to a second control arm by a partial loop and a second half frame having a first control arm connected to a second control arm by a partial loop. The partial loops cooperatively form a composite loop for attachment of a filtering element which will expand in the body vessel to capture embolic debris entrained in the fluid of the vessel. The lengths and positioning of the first and second control arms of each half frame can be varied to create an expandable frame which conforms to the size and shape of the body vessel in which the filtering device is deployed. Additionally, the radius of the partial loops, along with the length of the arc of the partial loops, can be varied on each of the frames to create a composite filtering assembly that can easily adapt to the size and shape of the body vessel. Additionally, the control arms of the half frames can be disposed either proximally or distally of the composite loop to create a distinct filtering structure.

    摘要翻译： 用于捕获身体血管中的栓塞碎片的栓塞过滤装置的可膨胀框架包括：第一半框架，具有通过部分回路连接到第二控制臂的第一控制臂，以及具有连接到第二控制臂的第二控制臂的第二半框架 第二控制臂通过部分回路。 部分回路协同地形成用于附接过滤元件的复合回路，该过滤元件将在体内容器中膨胀以捕获携带在血管流体中的栓塞碎片。 可以改变每个半框架的第一和第二控制臂的长度和定位，以便产生符合过滤装置展开的身体容器的尺寸和形状的可扩张框架。 此外，部分回路的半径以及部分回路的圆弧的长度可以在每个框架上变化以产生可以容易地适应身体血管的尺寸和形状的复合过滤组件。 此外，半框架的控制臂可以在复合环路的近侧或远端设置，以产生不同的过滤结构。

    Variable stiffness stent
    6.
    发明授权
    Variable stiffness stent 有权
    可变刚度支架

    公开(公告)号：US06652576B1

    公开(公告)日：2003-11-25

    申请号：US09590307

    申请日：2000-06-07

    申请人： Kent C. B. Stalker

    发明人： Kent C. B. Stalker

    IPC分类号： A61F206

    CPC分类号： A61F2/915 ,  A61F2/91 ,  A61F2002/91516 ,  A61F2002/91525 ,  A61F2002/91533 ,  A61F2002/91575 ,  A61F2250/0018

    摘要： A stent having a structure differentiated in terms of its stiffness. Such differentiation is achieved with the use of a superelastic material that transitions between a relatively soft and malleable phase to a stiffer phase at a transition temperature that is adjustable. By differentially adjusting the transition temperature of different portions of the stent, a differentiation of the stiffness of the structure is achieved upon the stent being subjected to body temperature.

    摘要翻译： 具有在其刚度方面不同的结构的支架。 这种分化是通过使用在可调节的转变温度下在相对柔软和可延展的相之间转变成更硬相的超弹性材料来实现的。 通过差异调节支架的不同部分的转变温度，在支架经受体温后实现结构刚度的分化。

    Device for, and method of, blocking emboli in vessels such as blood arteries
    9.
    发明授权
    Device for, and method of, blocking emboli in vessels such as blood arteries 有权
    阻塞栓塞血栓如血管的装置和方法

    公开(公告)号：US07918820B2

    公开(公告)日：2011-04-05

    申请号：US12557609

    申请日：2009-09-11

    申请人： Kent C. B. Stalker

    发明人： Kent C. B. Stalker

    IPC分类号： A61M29/00

    CPC分类号： A61F2/013 ,  A61F2/95 ,  A61F2/958 ,  A61F2/966 ,  A61F2002/018 ,  A61F2230/0006 ,  A61F2230/0067 ,  A61F2230/008

    摘要： A filtering device has a directional member and filtering member disposable in a vessel (e.g. blood artery) at a position past a lesion in the direction of fluid flow. The filtering member is made from a resilient material having properties of passing the fluid while blocking the passage of emboli in the fluid. This material may be selected from a group consisting of blood filter material and a braided/woven biocompatible material with the properties specified above. The inner end of the filtering member is attached to a shaft which provides for the disposition of the members in the vessel at the position past the lesion and the withdrawal of the members from the vessel. The directional member has a length extending at least to the vessel wall. The directional member is made from a pliable and elongatable material with properties of blocking fluid and emboli passage. The directional member is deployable within the vessel by the fluid flow in the vessel and directs the fluid in the vessel and any emboli in the fluid into the filtering member. The filtering and directional members are disposed at an acute angle relative to the shaft to create a trapping pocket. Restraining wires attached to the directional member are used to collapse the directional member and draw at least a part of the directional member into an outer sheath to prevent emboli from backflowing into the vessel.

    摘要翻译： 过滤装置具有定向构件和过滤构件，其在流体流动方向上的病变位置处的容器（例如血液动脉）中一次性使用。 过滤构件由弹性材料制成，其具有使流体通过的特性，同时阻止栓塞在流体中的通过。 该材料可以选自具有上述性质的血液过滤材料和编织/机织生物相容性材料。 过滤构件的内端附接到轴，其提供在容器中处于通过病变处的位置处的构件的位置并且将构件从容器中取出。 定向构件具有至少延伸到血管壁的长度。 定向构件由柔韧且可伸长的材料制成，具有堵塞流体和栓塞通道的特性。 定向构件可以通过容器中的流体流动在容器内展开，并将容器中的流体和流体中的任何栓塞引导到过滤构件中。 过滤和定向构件相对于轴设置成锐角以产生捕集袋。 连接到定向构件的限制线用于折叠定向构件并将定向构件的至少一部分拉入外护套以防止栓塞回流到容器中。

    DEVICE FOR, AND METHOD OF, BLOCKING EMBOLI IN VESSELS SUCH AS BLOOD ARTERIES
    10.
    发明申请
    DEVICE FOR, AND METHOD OF, BLOCKING EMBOLI IN VESSELS SUCH AS BLOOD ARTERIES 有权
    用于将血管阻塞在血管中作为血液动物的装置和方法

    公开(公告)号：US20100004674A1

    公开(公告)日：2010-01-07

    申请号：US12557609

    申请日：2009-09-11

    申请人： Kent C. B. Stalker

    发明人： Kent C. B. Stalker

    IPC分类号： A61F2/01

    CPC分类号： A61F2/013 ,  A61F2/95 ,  A61F2/958 ,  A61F2/966 ,  A61F2002/018 ,  A61F2230/0006 ,  A61F2230/0067 ,  A61F2230/008

    摘要： A filtering device has a directional member and filtering member disposable in a vessel (e.g. blood artery) at a position past a lesion in the direction of fluid flow. The filtering member is made from a resilient material having properties of passing the fluid while blocking the passage of emboli in the fluid. This material may be selected from a group consisting of blood filter material and a braided/woven biocompatible material with the properties specified above. The inner end of the filtering member is attached to a shaft which provides for the disposition of the members in the vessel at the position past the lesion and the withdrawal of the members from the vessel. The directional member has a length extending at least to the vessel wall. The directional member is made from a pliable and elongatable material with properties of blocking fluid and emboli passage. The directional member is deployable within the vessel by the fluid flow in the vessel and directs the fluid in the vessel and any emboli in the fluid into the filtering member. The filtering and directional members are disposed at an acute angle relative to the shaft to create a trapping pocket. Restraining wires attached to the directional member are used to collapse the directional member and draw at least a part of the directional member into an outer sheath to prevent emboli from backflowing into the vessel.

    摘要翻译： 过滤装置具有定向构件和过滤构件，其在流体流动方向上的病变位置处的容器（例如血液动脉）中一次性使用。 过滤构件由弹性材料制成，其具有使流体通过的特性，同时阻止栓塞在流体中的通过。 该材料可以选自具有上述性质的血液过滤材料和编织/机织生物相容性材料。 过滤构件的内端附接到轴，其提供在容器中处于通过病变处的位置处的构件的位置并且将构件从容器中取出。 定向构件具有至少延伸到血管壁的长度。 定向构件由柔韧且可伸长的材料制成，具有堵塞流体和栓塞通道的特性。 定向构件可以通过容器中的流体流动在容器内展开，并将容器中的流体和流体中的任何栓塞引导到过滤构件中。 过滤和定向构件相对于轴设置成锐角以产生捕集袋。 连接到定向构件的限制线用于折叠定向构件并将定向构件的至少一部分拉入外护套以防止栓塞回流到容器中。