公开(公告)号：US11358996B2

公开(公告)日：2022-06-14

申请号：US16711821

申请日：2019-12-12

申请人： WISCONSIN ALUMNI RESEARCH FOUNDATION

发明人： Daniel Butz ,  Zhouzheng Ren ,  Alexis Jo Piepenburg ,  Mark Eric Cook

IPC分类号： A61K38/18 ,  C07K14/50 ,  A61K47/64 ,  A61K39/385 ,  A61K39/00 ,  C07K16/22

摘要： Described herein are FGF-23 epitope peptides, methods of producing antibodies in laying hens by injecting the peptides, and methods of improving resistance to eggshell breakage and/or increasing eggshell strength by administering an FGF-23 epitope peptide to a laying hen.

公开(公告)号：US10544197B2

公开(公告)日：2020-01-28

申请号：US15675022

申请日：2017-08-11

申请人： WISCONSIN ALUMNI RESEARCH FOUNDATION

发明人： Mark Eric Cook ,  Zhouzheng Ren ,  Alexis Jo Piepenburg ,  Daniel Butz

IPC分类号： C07K7/06 ,  C07K14/50 ,  A61K38/08 ,  A61K38/18 ,  A61K47/64 ,  A61K39/385 ,  A61K39/00

摘要： Described herein are FGF-23 epitope peptides, methods of producing antibodies in laying hens by injecting the peptides, and methods of improving resistance to eggshell breakage and/or increasing eggshell strength by administering an FGF-23 epitope peptide to a laying hen.

公开(公告)号：US20200148734A1

公开(公告)日：2020-05-14

申请号：US16711821

申请日：2019-12-12

申请人： WISCONSIN ALUMNI RESEARCH FOUNDATION

发明人： Daniel Butz ,  Zhouzheng Ren ,  Alexis Jo Piepenburg ,  Mark Eric Cook (deceased)

IPC分类号： C07K14/50 ,  A61K39/385 ,  A61K38/18 ,  A61K47/64 ,  C07K16/22 ,  A61K39/00

摘要： Described herein are FGF-23 epitope peptides, methods of producing antibodies in laying hens by injecting the peptides, and methods of improving resistance to eggshell breakage and/or increasing eggshell strength by administering an FGF-23 epitope peptide to a laying hen.

公开(公告)号：US20180044390A1

公开(公告)日：2018-02-15

申请号：US15675022

申请日：2017-08-11

申请人： WISCONSIN ALUMNI RESEARCH FOUNDATION

发明人： Mark Eric Cook ,  Zhouzheng Ren ,  Alexis Jo Piepenburg ,  Daniel Butz

IPC分类号： C07K14/50 ,  A61K38/18 ,  A61K39/385 ,  A61K47/64

CPC分类号： C07K14/50 ,  A61K38/1825 ,  A61K39/0005 ,  A61K39/385 ,  A61K47/64 ,  A61K47/643 ,  A61K47/646 ,  A61K2039/54 ,  A61K2039/552 ,  A61K2039/62 ,  C07K16/22

摘要： Described herein are FGF-23 epitope peptides, methods of producing antibodies in laying hens by injecting the peptides, and methods of improving resistance to eggshell breakage and/or increasing eggshell strength by administering an FGF-23 epitope peptide to a laying hen.