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公开(公告)号:US06683057B1
公开(公告)日:2004-01-27
申请号:US09400861
申请日:1999-09-21
IPC分类号: A01N4304
CPC分类号: C12N9/1205 , A61K31/70 , A61K38/45 , A61K48/00 , C12N2799/022
摘要: The present invention relates, in general, to vascular smooth muscle proliferation and, in particular, to a method of inhibiting arterial and venous smooth muscle proliferation resulting, for example, from arterial injury or vein grafting. The invention also relates to an expression construct encoding a G&bgr;&ggr; inhibitor suitable for use in such a method.
摘要翻译: 本发明一般涉及血管平滑肌增生,特别涉及抑制动脉和静脉平滑肌增生的方法,其导致例如动脉损伤或静脉移植。 本发明还涉及编码适用于这种方法的Gbetagamma抑制剂的表达构建体。
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公开(公告)号:US5981487A
公开(公告)日:1999-11-09
申请号:US943208
申请日:1997-10-03
IPC分类号: G01N33/50 , A61K31/70 , A61K35/76 , A61K38/00 , A61K38/45 , A61K45/00 , A61K48/00 , A61P9/00 , C12N5/10 , C12N7/00 , C12N9/12 , C12N15/09 , G01N33/15
CPC分类号: C12N9/1205 , A61K31/70 , A61K38/45 , A61K48/00 , C12N2799/022
摘要: The present invention relates, in general, to vascular smooth muscle proliferation and, in particular, to a method of inhibiting arterial and venous smooth muscle proliferation resulting, for example, from arterial injury or vein grafting. The invention also relates to an expression construct encoding a G.beta..gamma. inhibitor suitable for use in such a method.
摘要翻译: 本发明一般涉及血管平滑肌增生,特别涉及抑制动脉和静脉平滑肌增生的方法,其导致例如动脉损伤或静脉移植。 本发明还涉及编码适用于这种方法的Gβγ抑制剂的表达构建体。
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