-
公开(公告)号:US07060688B2
公开(公告)日:2006-06-13
申请号:US10028726
申请日:2001-12-21
CPC分类号: C12N15/8509 , A01K67/0276 , A01K2217/05 , A01K2217/075 , A01K2227/105 , A01K2267/0331 , A61K38/00 , A61K48/00 , C07K14/47 , C07K16/18 , C12N9/16 , C12N2799/026 , G01N33/574
摘要: A method for gene therapy for cancers wherein chromosomal location of an inactive or defective cancer suppressing gene is established, a replacement gene which is preferably cloned is then used to replace the inactive or defective cancer suppressing gene in the chromosome. In addition to its uses in therapy, the present invention provides a means for prophylactically treating individuals having a genetic predisposition to cancer and provides an animal model for testing for carcinogenicity of environmental substances.