-
公开(公告)号:US20060019974A1
公开(公告)日:2006-01-26
申请号:US10380908
申请日:2001-09-17
申请人: Werner Mederski , Ralf Devant , Maria Devant , Gerhard Barnickel , Sabine Bernotat-Danielowski , James Vickers , Bertram Cezanne , Daljit Dhanoa , Bao-Ping Zhao , James Rinker , Mark Player , Edward Jaeger , Richard Soll
发明人: Werner Mederski , Ralf Devant , Maria Devant , Gerhard Barnickel , Sabine Bernotat-Danielowski , James Vickers , Bertram Cezanne , Daljit Dhanoa , Bao-Ping Zhao , James Rinker , Mark Player , Edward Jaeger , Richard Soll
IPC分类号: A61K31/517 , C07D403/02 , C07D239/94
CPC分类号: C07D239/94 , C07D239/95 , C07D401/12 , C07D403/12 , C07D405/12 , C07D409/04 , C07D409/14
摘要: Quinazolines of the formula (I) in which R, R1, R2, R3, R4 and Y have the meaning indicated in Patent claim 1, and their salts or solvates as glycoprotein IbIX antagonists.
摘要翻译: 式(I)的喹唑啉其中R 1,R 2,R 2,R 3,R 4, 并且Y具有专利权利要求1中所示的含义,并且其盐或溶剂合物作为糖蛋白IbIX拮抗剂。
-
公开(公告)号:US20060229339A1
公开(公告)日:2006-10-12
申请号:US10489960
申请日:2002-08-12
申请人: Henning Böttcher , Ralf Devant , Maria Devant , Gerd Bartoszyk , Hermann Russ , Frank Weber , Christoph Seyfried
发明人: Henning Böttcher , Ralf Devant , Maria Devant , Gerd Bartoszyk , Hermann Russ , Frank Weber , Christoph Seyfried
IPC分类号: A61K31/4433
CPC分类号: C07D405/12
摘要: Compounds of formula I in which R has a meaning as indicated in claim 1, or one of their optical isomers or pharmaceutically acceptable salts, used for the treatment of extrapyramidal movement disorders and/or adverse effects in extrapyramidal movement disorders and/or for the treatment of extrapyramidal symptoms (EPS) induced by neuroleptics.
摘要翻译: 其中R具有权利要求1所述含义的式I化合物或其用于治疗锥体束外运动障碍和/或锥体外系运动障碍和/或治疗中的副作用的其旋光异构体或药学上可接受的盐之一 的精神分裂症引起的锥体外系症状(EPS)。
-