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公开(公告)号:US20060229336A1
公开(公告)日:2006-10-12
申请号:US10538144
申请日:2003-12-12
申请人: Wieslaw Kazmierski , Chrisopher Aquino , Neil Bifulco , Eric Boros , Brian Chauder , Pek Chong , Maosheng Duan , Felix Deanda , Cecilia Koble , Ed Mclean , Jennifer Peckham , Angilique Perkins , James Thompson , Dana Vanderwall
发明人: Wieslaw Kazmierski , Chrisopher Aquino , Neil Bifulco , Eric Boros , Brian Chauder , Pek Chong , Maosheng Duan , Felix Deanda , Cecilia Koble , Ed Mclean , Jennifer Peckham , Angilique Perkins , James Thompson , Dana Vanderwall
IPC分类号: A61K31/454 , C07D403/02 , C07D211/32
CPC分类号: C07D451/04
摘要: The present invention relates to compounds of formula (I) or a pharmaceutically acceptable derivatives thereof, useful in the treatment of prophylazis of CCR5-related diseases and disorders, for example, in the inhibition of HIV replication, the prevention or treatment of HIV infection, and in the treatment of the resulting acquired immune deficiency syndrome (AIDS).
摘要翻译: 本发明涉及式(I)化合物或其药学上可接受的衍生物,其可用于治疗CCR5相关疾病和病症的预防,例如抑制HIV复制,预防或治疗HIV感染, 以及治疗所得的获得性免疫缺陷综合征(AIDS)。