公开(公告)号：US08956520B2

公开(公告)日：2015-02-17

申请号：US13322702

申请日：2010-06-03

申请人： Wilhelmus Joannes Theodorus Maria Appelman ,  Hans Lammers ,  Arie Volmer ,  Tjerk Oedse Boonstra ,  Adrianus Maria Reichwein

发明人： Wilhelmus Joannes Theodorus Maria Appelman ,  Hans Lammers ,  Arie Volmer ,  Tjerk Oedse Boonstra ,  Adrianus Maria Reichwein

IPC分类号： B01D61/44 ,  C07C227/18

CPC分类号： C07C227/18 ,  B01D61/44 ,  C07C229/16

摘要： The present invention relates to a process comprising the reaction of a cyanide with a hydrogen cyanide-reactive compound, characterized in that the cyanide is a cyanide salt and the process is an electrochemical process involving the transporting of a reaction mixture to which cyanide salt has been added through an electrochemical cell, in which process the cyanide salt reacts with the hydrogen cyanide-reactive compound while at least partly under the influence of an electric current the cyanide salt is acidified and the salt cation content is reduced.

摘要翻译： 本发明涉及一种包括氰化物与氰化氢反应性化合物的反应的方法，其特征在于氰化物是氰化物盐，该方法是一种电化学方法，涉及运输已经将氰化物盐的反应混合物 通过电化学电池添加，其中氰化物盐与氰化氢反应性化合物反应，同时至少部分地在电流的影响下，氰化物盐被酸化并且盐阳离子含量降低。

公开(公告)号：US08551312B2

公开(公告)日：2013-10-08

申请号：US12516911

申请日：2007-11-27

申请人： Martin Heus ,  Hans Lammers ,  Arie Volmer

发明人： Martin Heus ,  Hans Lammers ,  Arie Volmer

IPC分类号： B01D61/42

CPC分类号： C07C227/40 ,  B01D61/44 ,  C07C229/16 ,  C07C229/24

摘要： The invention relates to a process for the production of an amino acid having at least one secondary or tertiary amino group and three or more carboxyl groups or its salt with less than an equivalent of alkaline metal based on the number of carboxyl groups, said process comprising reducing alkali metal ions from an aqueous solution of an alkali metal salt of an amino acid having at least one secondary or tertiary amino group and three or more carboxyl groups and acidifying the amino carboxylate starting material by first performing a chemical acidification step using an organic or inorganic acid to get a compound in which at least one of the groups is protonated, and in a subsequent step further acidifying the amino carboxylate starting material and reducing alkali metal ions from an aqueous solution of the partially acidified alkali metal salt of the amino acid having at least one secondary or tertiary amino group and three or more carboxyl groups by electrodialysis, wherein the electrodialysis is performed using a hydrogen ion permselective membrane on the anode side and a cation-permeable membrane on the cathode side.

摘要翻译： 本发明涉及一种制备具有至少一个仲氨基或叔氨基和三个或更多个羧基的氨基酸的方法或其盐，其基于羧基数目少于等于碱当量，所述方法包括 从具有至少一个仲或叔氨基和三个或多个羧基的氨基酸的碱金属盐的水溶液中还原碱金属离子，并且通过首先使用有机或不饱和羧酸盐进行化学酸化步骤酸化氨基羧酸盐原料 无机酸，得到其中至少一个基团被质子化的化合物，并且在随后的步骤中，进一步酸化氨基羧酸酯起始原料并从部分酸化的氨基酸的碱金属盐的水溶液中还原碱金属离子，其具有 至少一个仲或叔氨基和三个或更多个羧基通过电渗析，其中选 使用阳极侧的氢离子选择性膜和阴极侧的阳离子透过膜进行透析。

公开(公告)号：US20100126864A1

公开(公告)日：2010-05-27

申请号：US12516911

申请日：2007-11-27

申请人： Martin Heus ,  Hans Lammers ,  Arie Volmer

发明人： Martin Heus ,  Hans Lammers ,  Arie Volmer

IPC分类号： C07C227/40

CPC分类号： C07C227/40 ,  B01D61/44 ,  C07C229/16 ,  C07C229/24

摘要： The invention relates to a process for the production of an amino acid having at least one secondary or tertiary amino group and three or more carboxyl groups or its salt with less than an equivalent of alkaline metal based on the number of carboxyl groups, said process comprising reducing alkali metal ions from an aqueous solution of an alkali metal salt of an amino acid having at least one secondary or tertiary amino group and three or more carboxyl groups and acidifying the amino carboxylate starting material by first performing a chemical acidification step using an organic or inorganic acid to get a compound in which at least one of the groups is protonated, and in a subsequent step further acidifying the amino carboxylate starting material and reducing alkali metal ions from an aqueous solution of the partially acidified alkali metal salt of the amino acid having at least one secondary or tertiary amino group and three or more carboxyl groups by electrodialysis, wherein the electrodialysis is performed using a hydrogen ion permselective membrane on the anode side and a cation-permeable membrane on the cathode side.

摘要翻译： 本发明涉及一种制备具有至少一个仲氨基或叔氨基和三个或更多个羧基的氨基酸的方法或其盐，其基于羧基数目少于等于碱当量，所述方法包括 从具有至少一个仲或叔氨基和三个或多个羧基的氨基酸的碱金属盐的水溶液中还原碱金属离子，并且通过首先使用有机或不饱和羧酸盐进行化学酸化步骤酸化氨基羧酸盐原料 无机酸，得到其中至少一个基团被质子化的化合物，并且在随后的步骤中，进一步酸化氨基羧酸酯起始原料并从部分酸化的氨基酸的碱金属盐的水溶液中还原碱金属离子，其具有 至少一个仲或叔氨基和三个或更多个羧基通过电渗析，其中选 使用阳极侧的氢离子选择性膜和阴极侧的阳离子透过膜进行透析。