公开(公告)号：US07773790B2

公开(公告)日：2010-08-10

申请号：US11530110

申请日：2006-09-08

申请人： William Cork ,  Tim Patno ,  Mark Weber ,  Dave Morrow ,  Wesley Buckingham

发明人： William Cork ,  Tim Patno ,  Mark Weber ,  Dave Morrow ,  Wesley Buckingham

IPC分类号： G06K9/00

CPC分类号： G01N33/54346 ,  G01N21/253

摘要： An apparatus and method for imaging metallic nanoparticles is provided. Preferably, the invention provides for an apparatus and method for detection of gold colloid particles and for accurate reporting to the operator. The apparatus includes a substrate holder for holding the substrate, a processor and memory device, an imaging module, an illumination module, a power module, an input module, and an output module. The apparatus may have a stationary substrate holder and imaging module which are proximate to one another. The apparatus provided for a compact sized system without the need for complex motorized devices to move the camera across the substrate. Further, the apparatus and method provide for automatic detection of the spots/wells on the substrate, automatic quantification of the spots on the substrate, and automatic interpretation of the spots based on decision statistics.

摘要翻译： 提供了一种用于成像金属纳米颗粒的设备和方法。 优选地，本发明提供了用于检测金胶体颗粒并且准确地向操作者报告的装置和方法。 该装置包括用于保持基板的基板支架，处理器和存储装置，成像模块，照明模块，电源模块，输入模块和输出模块。 该装置可以具有彼此靠近的固定衬底保持器和成像模块。 该设备提供了一种紧凑型系统，而不需要复杂的电动装置来使相机移动穿过基板。 此外，该装置和方法提供对基板上的点/孔的自动检测，基板上的点的自动定量，以及基于判定统计的斑点的自动解释。

公开(公告)号：US20100033724A1

公开(公告)日：2010-02-11

申请号：US12355534

申请日：2009-01-16

申请人： William Cork ,  Tim Patno ,  Mark Weber ,  Dave Morrow ,  Wesley Buckingham

发明人： William Cork ,  Tim Patno ,  Mark Weber ,  Dave Morrow ,  Wesley Buckingham

IPC分类号： G01N21/55

CPC分类号： G01N21/552 ,  G01N21/47 ,  G01N33/54346 ,  G01N33/54373 ,  G01N2015/0038

摘要： An apparatus and method for imaging metallic nanoparticles. The invention teaches an apparatus and method for detection of gold colloid particles and for accurate reporting to the operator. The apparatus includes a substrate holder for holding the substrate, a processor and memory device, an imaging module, and illumination module, an input module, and an output module. The apparatus may have a stationary substrate holder and imaging module which are proximate to one another. The apparatus provides for a compact system without the need for complex motorized devices to move a camera across the substrate. Further, the apparatus and method provide for automatic detection of the spots/wells on the substrate, automatic quantification of the spots on the substrate, and automatic interpretation of the spots based on decision statistics.

摘要翻译： 用于金属纳米颗粒成像的装置和方法。 本发明教导了用于检测金胶体颗粒并且准确地向操作者报告的装置和方法。 该装置包括用于保持基板的基板保持器，处理器和存储器件，成像模块和照明模块，输入模块和输出模块。 该装置可以具有彼此靠近的固定衬底保持器和成像模块。 该装置提供紧凑的系统，而不需要复杂的电动装置来移动照相机跨越衬底。 此外，该装置和方法提供对基板上的点/孔的自动检测，基板上的点的自动定量，以及基于判定统计的斑点的自动解释。

公开(公告)号：US20120063653A1

公开(公告)日：2012-03-15

申请号：US12853047

申请日：2010-08-09

申请人： William Cork ,  Tim Patno ,  Mark Weber ,  Dave Morrow ,  Wesley Buckingham

发明人： William Cork ,  Tim Patno ,  Mark Weber ,  Dave Morrow ,  Wesley Buckingham

IPC分类号： G06K9/00

CPC分类号： G01N33/54346 ,  G01N21/253

摘要： An apparatus and method for imaging metallic nanoparticles is provided. Preferably, the invention provides for an apparatus and method for detection of gold colloid particles and for accurate reporting to the operator. The apparatus includes a substrate holder for holding the substrate, a processor and memory device, an imaging module, an illumination module, a power module, an input module, and an output module. The apparatus may have a stationary substrate holder and imaging module which are proximate to one another. The apparatus provided for a compact sized system without the need for complex motorized devices to move the camera across the substrate. Further, the apparatus and method provide for automatic detection of the spots/wells on the substrate, automatic quantification of the spots on the substrate, and automatic interpretation of the spots based on decision statistics.

摘要翻译： 提供了一种用于成像金属纳米颗粒的设备和方法。 优选地，本发明提供了用于检测金胶体颗粒并且准确地向操作者报告的装置和方法。 该装置包括用于保持基板的基板支架，处理器和存储装置，成像模块，照明模块，电源模块，输入模块和输出模块。 该装置可以具有彼此靠近的固定衬底保持器和成像模块。 该设备提供了一种紧凑型系统，而不需要复杂的电动装置来使相机移动穿过基板。 此外，该装置和方法提供对基板上的点/孔的自动检测，基板上的点的自动定量，以及基于判定统计的斑点的自动解释。

公开(公告)号：US20070148665A1

公开(公告)日：2007-06-28

申请号：US11530138

申请日：2006-09-08

申请人： William Cork ,  Tim Patno ,  Mark Weber ,  Dave Morrow ,  Wesley Buckingham

发明人： William Cork ,  Tim Patno ,  Mark Weber ,  Dave Morrow ,  Wesley Buckingham

IPC分类号： C12Q1/68 ,  G06T7/00

CPC分类号： G01N33/54346 ,  G01N21/253

摘要： An apparatus and method for imaging metallic nanoparticles is provided. Preferably, the invention provides for an apparatus and method for detection of gold colloid particles and for accurate reporting to the operator. The apparatus includes a substrate holder for holding the substrate, a processor and memory device, an imaging module, an illumination module, a power module, an input module, and an output module. The apparatus may have a stationary substrate holder and imaging module which are proximate to one another. The apparatus provided for a compact sized system without the need for complex motorized devices to move the camera across the substrate. Further, the apparatus and method provide for automatic detection of the spots/wells on the substrate, automatic quantification of the spots on the substrate, and automatic interpretation of the spots based on decision statistics.

摘要翻译： 提供了一种用于成像金属纳米颗粒的设备和方法。 优选地，本发明提供了用于检测金胶体颗粒并且准确地向操作者报告的装置和方法。 该装置包括用于保持基板的基板支架，处理器和存储装置，成像模块，照明模块，电源模块，输入模块和输出模块。 该装置可以具有彼此靠近的固定衬底保持器和成像模块。 该设备提供了一种紧凑型系统，而不需要复杂的电动装置来使相机移动穿过基板。 此外，该装置和方法提供对基板上的点/孔的自动检测，基板上的点的自动定量，以及基于判定统计的斑点的自动解释。

公开(公告)号：US20070041624A1

公开(公告)日：2007-02-22

申请号：US11530110

申请日：2006-09-08

申请人： William Cork ,  Tim Patno ,  Mark Weber ,  Dave Morrow ,  Wesley Buckingham

发明人： William Cork ,  Tim Patno ,  Mark Weber ,  Dave Morrow ,  Wesley Buckingham

IPC分类号： G06K9/00

CPC分类号： G01N33/54346 ,  G01N21/253

摘要： An apparatus and method for imaging metallic nanoparticles is provided. Preferably, the invention provides for an apparatus and method for detection of gold colloid particles and for accurate reporting to the operator. The apparatus includes a substrate holder for holding the substrate, a processor and memory device, an imaging module, an illumination module, a power module, an input module, and an output module. The apparatus may have a stationary substrate holder and imaging module which are proximate to one another. The apparatus provided for a compact sized system without the need for complex motorized devices to move the camera across the substrate. Further, the apparatus and method provide for automatic detection of the spots/wells on the substrate, automatic quantification of the spots on the substrate, and automatic interpretation of the spots based on decision statistics.

摘要翻译： 提供了一种用于成像金属纳米颗粒的设备和方法。 优选地，本发明提供了用于检测金胶体颗粒并且准确地向操作者报告的装置和方法。 该装置包括用于保持基板的基板支架，处理器和存储装置，成像模块，照明模块，电源模块，输入模块和输出模块。 该装置可以具有彼此靠近的固定衬底保持器和成像模块。 该设备提供了一种紧凑型系统，而不需要复杂的电动装置来使相机移动穿过基板。 此外，该装置和方法提供对基板上的点/孔的自动检测，基板上的点的自动定量，以及基于判定统计的斑点的自动解释。

公开(公告)号：US07110585B2

公开(公告)日：2006-09-19

申请号：US10210959

申请日：2002-08-02

申请人： William Cork ,  Tim Patno ,  Mark Weber ,  Dave Morrow ,  Wesley Buckingham

发明人： William Cork ,  Tim Patno ,  Mark Weber ,  Dave Morrow ,  Wesley Buckingham

IPC分类号： G06K9/00

CPC分类号： G01N33/54346 ,  G01N21/253

摘要： An apparatus and method for imaging metallic nanoparticles is provided. Preferably, the invention provides for an apparatus and method for detection of gold colloid particles and for accurate reporting to the operator. The apparatus includes a substrate holder for holding the substrate, a processor and memory device, an imaging module, an illumination module, a power module, an input module, and an output module. The apparatus may have a stationary substrate holder and imaging module which are proximate to one another. The apparatus provided for a compact sized system without the need for complex motorized devices to move the camera across the substrate. Further, the apparatus and method provide for automatic detection of the spots/wells on the substrate, automatic quantification of the spots on the substrate, and automatic interpretation of the spots based on decision statistics.