公开(公告)号：US4829099A

公开(公告)日：1989-05-09

申请号：US74597

申请日：1987-07-17

申请人： William D. Fuller ,  Robert K. Blair ,  Murray Goodman

发明人： William D. Fuller ,  Robert K. Blair ,  Murray Goodman

IPC分类号： A61L26/00 ,  A61L24/04 ,  C08G18/16 ,  C08G18/18 ,  C08G18/20 ,  C08G18/77 ,  C09J175/00

CPC分类号： C09J175/00 ,  A61L24/046 ,  C08G18/16 ,  C08G18/1833 ,  C08G18/2018 ,  C08G18/771 ,  C08G2170/60 ,  C08G2230/00

摘要： Metabolically-acceptable, surgical adhesives are prepared from polyisocyanates having the structral formula: ##STR1## wherein R is a polyvalent aliphatic radical of about 1 to 10 carbon atoms or a polyvalent aromatic radical of 6 to about 24 carbon atoms;A is C, S or P;Z is O or S;Y is 1 when A is C or P, and 2 when A is S;n is 1 or 2;p is at least 1;q is 0 or 1, with the proviso that when A is carbon or sulfur, q is 0;r is 0 or 1, with the proviso that when A is carbon or sulfur, r is 0;X is a residue of an organic compound having active hydrogen-containing groups; andX' is a residue of an organic compound having at least 1 active hydrogen-containing group.

摘要翻译： 代谢可接受的手术粘合剂由具有以下结构式的多异氰酸酯制备：其中R是约1-10个碳原子的多价脂肪族基团或6至约24个碳原子的多价芳族基团; A是C，S或P; Z是O或S; 当A为C或P时，Y为1，A为S时为2; n为1或2; p至少为1; q为0或1，条件是当A为碳或硫时，q为0; r为0或1，条件是当A为碳或硫时，r为0; X是具有含活性氢基团的有机化合物的残基; X'是具有至少1个含活性氢基团的有机化合物的残基。