公开(公告)号：US20100272743A1

公开(公告)日：2010-10-28

申请号：US11655678

申请日：2007-01-19

申请人： William John Kimmerly

发明人： William John Kimmerly

IPC分类号： A61K39/085 ,  C07H21/04 ,  C07H21/02 ,  C07K14/00 ,  A61P37/04

CPC分类号： C07K14/31

摘要： S epidermidis polypeptides and DNA (RNA) encoding such polypeptides and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptides and DNA (RNA) for the treatment of infection, particularly infections arising from S epidermidis. Antagonists against the function of such polypeptides and their use as therapeutics to treat infection are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to the presence of S epidermidis nucleic acid sequences and the polypeptides in a host. Also disclosed are diagnostic assays for detecting polynucleotides and polypeptides related to S epidermidis

摘要翻译： 公开了S表皮多肽和编码这些多肽的DNA（RNA）以及通过重组技术产生此类多肽的方法。 还公开了利用这种多肽和DNA（RNA）来治疗感染，特别是表皮葡萄球菌引起的感染的方法。 还公开了抗这种多肽的功能的拮抗剂及其作为治疗剂治疗感染的用途。 还公开了用于检测与宿主中表皮葡萄球菌核酸序列和多肽存在相关的疾病的诊断测定法。 还公开了用于检测与S表皮相关的多核苷酸和多肽的诊断测定

公开(公告)号：US06703492B1

公开(公告)日：2004-03-09

申请号：US09710279

申请日：2000-11-09

申请人： William John Kimmerly

发明人： William John Kimmerly

IPC分类号： C12N120

CPC分类号： C07K14/31

摘要： S epidermidis polypeptides and DNA (RNA) encoding such polypeptides and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptides and DNA (RNA) for the treatment of infection, particularly infections arising from S epidermidis. Antagonists against the function of such polypeptides and their use as therapeutics to treat infection are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to the presence of S epidermidis nucleic acid sequences and the polypeptides in a host. Also disclosed are diagnostic assays for detecting polynucleotides and polypeptides related to S epidermidis.

摘要翻译： 公开了S表皮多肽和编码这些多肽的DNA（RNA）以及通过重组技术产生此类多肽的方法。 还公开了利用这些多肽和DNA（RNA）来治疗感染，特别是表皮葡萄球菌引起的感染的方法。 还公开了抗这种多肽的功能的拮抗剂及其作为治疗剂治疗感染的用途。 还公开了用于检测与宿主中表皮葡萄球菌核酸序列和多肽存在相关的疾病的诊断测定法。 还公开了用于检测与S表皮相关的多核苷酸和多肽的诊断测定。