公开(公告)号：US20230357819A1

公开(公告)日：2023-11-09

申请号：US18313150

申请日：2023-05-05

申请人： Wisconsin Alumni Research Foundation

发明人： Jo Handelsman ,  Marc Chevrette ,  Chris Thomas ,  Julia Nepper ,  Josephine Putnam

IPC分类号： C12Q1/18

CPC分类号： C12Q1/18

摘要： The present invention provides streamlined methods for identifying biologically active bacterial products. Products identified by these methods are also provided.

公开(公告)号：US11691145B2

公开(公告)日：2023-07-04

申请号：US17496409

申请日：2021-10-07

申请人： Wisconsin Alumni Research Foundation

发明人： David J. Beebe ,  Duane S. Juang ,  Jiaquan Yu ,  Jo Handelsman

IPC分类号： B01L3/00 ,  C12Q1/20 ,  C40B60/12

CPC分类号： B01L3/502715 ,  C12Q1/20 ,  C40B60/12 ,  B01L2300/087 ,  B01L2300/0848 ,  B01L2300/123

摘要： A platform and method for conducting multi-variable combinational interactions are provided. An array of multiplexing chambers in formed in a body. The body also includes a common well communicating with each multiplexing chamber of the array of multiplexing chambers and a plurality of variable wells. Each of variable wells communicates with at least one multiplexing chamber of the array of multiplexing chambers. The common well is loaded with a first variable and different variables are loaded in each of the plurality of variable wells. The interaction of the first variable with at least one of the different variables in each multiplexing chamber of the array of multiplexing chambers is observed.

公开(公告)号：US20220097058A1

公开(公告)日：2022-03-31

申请号：US17496409

申请日：2021-10-07

申请人： Wisconsin Alumni Research Foundation

发明人： David J. Beebe ,  Duane S. Juang ,  Jiaquan Yu ,  Jo Handelsman

IPC分类号： B01L3/00 ,  C12Q1/20 ,  C40B60/12

摘要： A platform and method for conducting multi-variable combinational interactions are provided. An array of multiplexing chambers in formed in a body. The body also includes a common well communicating with each multiplexing chamber of the array of multiplexing chambers and a plurality of variable wells. Each of variable wells communicates with at least one multiplexing chamber of the array of multiplexing chambers. The common well is loaded with a first variable and different variables are loaded in each of the plurality of variable wells. The interaction of the first variable with at least one of the different variables in each multiplexing chamber of the array of multiplexing chambers is observed.

公开(公告)号：US11185860B2

公开(公告)日：2021-11-30

申请号：US16217602

申请日：2018-12-12

申请人： Wisconsin Alumni Research Foundation

发明人： David J. Beebe ,  Duane S. Juang ,  Jiaquan Yu ,  Jo Handelsman

IPC分类号： B01L3/00 ,  C12Q1/20 ,  C40B60/12

摘要： A platform and method for conducting multi-variable combinational interactions are provided. An array of multiplexing chambers in formed in a body. The body also includes a common well communicating with each multiplexing chamber of the array of multiplexing chambers and a plurality of variable wells. Each of variable wells communicates with at least one multiplexing chamber of the array of multiplexing chambers. The common well is loaded with a first variable and different variables are loaded in each of the plurality of variable wells. The interaction of the first variable with at least one of the different variables in each multiplexing chamber of the array of multiplexing chambers is observed.