公开(公告)号：US11473146B2

公开(公告)日：2022-10-18

申请号：US16745608

申请日：2020-01-17

申请人： Wisconsin Alumni Research Foundation

发明人： Peter Muir ,  Susannah Sample ,  John Svaren

IPC分类号： C12Q1/6883

摘要： Methods for diagnosing propensity to exhibit acquired peripheral neuropathy in dogs are described. The methods and kits test dogs for presence of a disease-associated genomic variant. Presence of the genomic variant indicates an increased likelihood of the dog developing an acquired peripheral neuropathy. This information can be used to guide preemptive clinical treatment of the animal for peripheral neuropathy and to choose dogs for selective breeding programs.

公开(公告)号：US20170335398A1

公开(公告)日：2017-11-23

申请号：US15599730

申请日：2017-05-19

申请人： Wisconsin Alumni Research Foundation

发明人： Peter Muir ,  Susannah Sample ,  John Svaren

IPC分类号： C12Q1/68 ,  A01K67/02

摘要： Methods and kits for diagnosing propensity to exhibit acquired peripheral neuropathy in dogs are described. The methods and kits test dogs for presence of a single-nucleotide polymorphism (SNP) TIGRP2P18586_rs8746233. Presence of the SNP indicates an increased likelihood of the dog exhibiting an acquired peripheral neuropathy. This information can be used to guide preemptive clinical treatment of the animal for peripheral neuropathy and to choose dogs for selective breeding programs.

公开(公告)号：US20230014028A1

公开(公告)日：2023-01-19

申请号：US17946613

申请日：2022-09-16

申请人： Wisconsin Alumni Research Foundation

发明人： Peter Muir ,  Susannah Sample ,  John Svaren

IPC分类号： C12Q1/6883

摘要： Methods for diagnosing propensity to exhibit acquired peripheral neuropathy in dogs are described. The methods and kits test dogs for presence of a disease-associated genomic variant. Presence of the genomic variant indicates an increased likelihood of the dog developing an acquired peripheral neuropathy. This information can be used to guide preemptive clinical treatment of the animal for peripheral neuropathy and to choose dogs for selective breeding programs.

公开(公告)号：US20200232035A1

公开(公告)日：2020-07-23

申请号：US16745608

申请日：2020-01-17

申请人： Wisconsin Alumni Research Foundation

发明人： Peter Muir ,  Susannah Sample ,  John Svaren

IPC分类号： C12Q1/6883

摘要： Methods for diagnosing propensity to exhibit acquired peripheral neuropathy in dogs are described. The methods and kits test dogs for presence of a disease-associated genomic variant. Presence of the genomic variant indicates an increased likelihood of the dog developing an acquired peripheral neuropathy. This information can be used to guide preemptive clinical treatment of the animal for peripheral neuropathy and to choose dogs for selective breeding programs.

公开(公告)号：US12098427B2

公开(公告)日：2024-09-24

申请号：US17946613

申请日：2022-09-16

申请人： Wisconsin Alumni Research Foundation

发明人： Peter Muir ,  Susannah Sample ,  John Svaren

IPC分类号： C12Q1/6883

CPC分类号： C12Q1/6883 ,  C12Q2600/156

摘要： Methods for diagnosing propensity to exhibit acquired peripheral neuropathy in dogs are described. The methods and kits test dogs for presence of a disease-associated genomic variant. Presence of the genomic variant indicates an increased likelihood of the dog developing an acquired peripheral neuropathy. This information can be used to guide preemptive clinical treatment of the animal for peripheral neuropathy and to choose dogs for selective breeding programs.

公开(公告)号：US10724098B2

公开(公告)日：2020-07-28

申请号：US15599730

申请日：2017-05-19

申请人： Wisconsin Alumni Research Foundation

发明人： Peter Muir ,  Susannah Sample ,  John Svaren

IPC分类号： C12Q1/68 ,  C07H21/04 ,  C12Q1/6883 ,  A01K67/02

摘要： Methods and kits for diagnosing propensity to exhibit acquired peripheral neuropathy in dogs are described. The methods and kits test dogs for presence of a single-nucleotide polymorphism (SNP) TIGRP2P18586_rs8746233. Presence of the SNP indicates an increased likelihood of the dog exhibiting an acquired peripheral neuropathy. This information can be used to guide preemptive clinical treatment of the animal for peripheral neuropathy and to choose dogs for selective breeding programs.