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公开(公告)号：US11059815B2
公开(公告)日：2021-07-13
申请号：US16800514
申请日：2020-02-25
Applicant: Wisconsin Alumni Research Foundation
Inventor： Weiping Tang , Ka Yang , Hao Wu , Zhongrui Zhang
IPC: C07D417/14 , C07D401/14
Abstract: Histone deacetylase (“HDAC”)-selective inhibitors covalently bonded to a linker covalently bonded to an E3 ubiquitin ligase ligand, and salts thereof; pharmaceutical compositions containing them; methods of using the composition to inhibit neoplastic cell growth in mammals, including humans.
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