-
1.
公开(公告)号:US20130293884A1
公开(公告)日:2013-11-07
申请号:US13986424
申请日:2013-05-01
申请人: Woonjoo Lee , Seung Yong Lee , Oded Rabin , Robert M. Briber , Xin Zhang
发明人: Woonjoo Lee , Seung Yong Lee , Oded Rabin , Robert M. Briber , Xin Zhang
CPC分类号: G01N21/01 , B05D3/10 , B05D3/101 , G01N21/648 , G01N21/658 , Y10T428/24893
摘要: The present invention is directed to self-assembled nanoparticle arrays, methods of making the nanoparticle arrays, and methods of using the nanoparticle arrays in spectroscopic methods for detecting targets of interest. The present invention is also directed to a fabrication method for surface-enhanced Raman scattering (SERS) substrates that possess a unique combination of three highly desirable attributes: (a) the SERS substrates can be tuned to match the laser wavelength of operation and maximize the enhancement factor for the particular Raman instrument and analyte in use; (b) the SERS substrates have a highly reproducible enhancement factor over macroscopic sampling areas; and (c) the fabrication method is achieved without resorting to expensive, slow nano-lithography tools.
摘要翻译: 本发明涉及自组装纳米颗粒阵列,制备纳米颗粒阵列的方法,以及在用于检测目的靶的光谱方法中使用纳米颗粒阵列的方法。 本发明还涉及一种用于表面增强拉曼散射(SERS)衬底的制造方法,其具有三种非常理想属性的独特组合:(a)可以调整SERS衬底以匹配操作的激光波长并使 特定拉曼仪器和分析物在使用中的增强因子; (b)SERS底物在宏观取样区域具有高度可重现的增强因子; 和(c)制造方法是在不使用昂贵,缓慢的纳米光刻工具的情况下实现的。
-
公开(公告)号:US09279759B2
公开(公告)日:2016-03-08
申请号:US13986424
申请日:2013-05-01
申请人: Woonjoo Lee , Seung Yong Lee , Oded Rabin , Robert M. Briber , Xin Zhang
发明人: Woonjoo Lee , Seung Yong Lee , Oded Rabin , Robert M. Briber , Xin Zhang
CPC分类号: G01N21/01 , B05D3/10 , B05D3/101 , G01N21/648 , G01N21/658 , Y10T428/24893
摘要: The present invention is directed to self-assembled nanoparticle arrays, methods of making the nanoparticle arrays, and methods of using the nanoparticle arrays in spectroscopic methods for detecting targets of interest. The present invention is also directed to a fabrication method for surface-enhanced Raman scattering (SERS) substrates that possess a unique combination of three highly desirable attributes: (a) the SERS substrates can be tuned to match the laser wavelength of operation and maximize the enhancement factor for the particular Raman instrument and analyte in use; (b) the SERS substrates have a highly reproducible enhancement factor over macroscopic sampling areas; and (c) the fabrication method is achieved without resorting to expensive, slow nano-lithography tools.
-