公开(公告)号：US09481677B2

公开(公告)日：2016-11-01

申请号：US14355549

申请日：2012-10-30

Applicant: XENON PHARMACEUTICALS INC.

Inventor： Shifeng Liu ,  Thilo Focken ,  Navjot Chahal ,  Zaihui Zhang ,  Renata Marcella Oballa ,  Julia Fonarev

IPC: C07D487/04 ,  C07D417/12 ,  C07D471/04 ,  C07D473/00 ,  C07D417/14 ,  C07D403/12

CPC classification number: C07D487/04 ,  C07D403/12 ,  C07D417/12 ,  C07D417/14 ,  C07D471/04 ,  C07D473/00

Abstract: This invention is directed to biaryl ether sulfonamides, or pharmaceutically acceptable salts, solvates or prodrugs thereof, for the treatment and/or prevention of sodium channel-mediated diseases or conditions, such as pain.

Abstract translation: 本发明涉及用于治疗和/或预防钠通道介导的疾病或病症例如疼痛的联芳基醚磺酰胺或其药学上可接受的盐，溶剂合物或前药。

公开(公告)号：US20140256736A1

公开(公告)日：2014-09-11

申请号：US14355549

申请日：2012-10-30

Applicant: XENON PHARMACEUTICALS INC.

Inventor： Shifeng Liu ,  Thilo Focken ,  Navjot Chahal ,  Zaihui Zhang ,  Renata Marcella Oballa ,  Julia Fonarev

IPC: C07D487/04 ,  C07D417/12 ,  C07D471/04

CPC classification number: C07D487/04 ,  C07D403/12 ,  C07D417/12 ,  C07D417/14 ,  C07D471/04 ,  C07D473/00

Abstract: This invention is directed to biaryl ether sulfonamides, or pharmaceutically acceptable salts, solvates or prodrugs thereof, for the treatment and/or prevention of sodium channel-mediated diseases or conditions, such as pain.

Abstract translation: 本发明涉及用于治疗和/或预防钠通道介导的疾病或病症如疼痛的联芳基醚磺酰胺或其药学上可接受的盐，溶剂合物或前药。

公开(公告)号：US09365578B2

公开(公告)日：2016-06-14

申请号：US14355549

申请日：2012-10-30

Applicant: XENON PHARMACEUTICALS INC.

Inventor： Shifeng Liu ,  Thilo Focken ,  Navjot Chahal ,  Zaihui Zhang ,  Renata Marcella Oballa ,  Julia Fonarev

IPC: C07D487/04 ,  C07D417/12 ,  C07D471/04 ,  C07D473/00 ,  C07D417/14 ,  C07D403/12

Abstract: This invention is directed to biaryl ether sulfonamides, or pharmaceutically acceptable salts, solvates or prodrugs thereof, for the treatment and/or prevention of sodium channel-mediated diseases or conditions, such as pain.