公开(公告)号：US10131894B2

公开(公告)日：2018-11-20

申请号：US14768126

申请日：2015-08-07

Applicant: XYLECO, INC.

Inventor： Marshall Medoff ,  Natasha Kreder ,  James J. Lynch ,  Sean Landry ,  Aiichiro Yoshida ,  Desiree Pangilinan ,  Thomas Craig Masterman

IPC: C12N9/42 ,  C12P19/02 ,  C12P19/14

Abstract: The present invention relates to compositions comprising an aglycosylated polypeptide having cellobiase activity, and methods for producing and using the same.

公开(公告)号：US20190024068A1

公开(公告)日：2019-01-24

申请号：US16151690

申请日：2018-10-04

Applicant: XYLECO, INC.

Inventor： Marshall Medoff ,  Natasha Kreder ,  James J. Lynch ,  Sean Landry ,  Aiichiro Yoshida ,  Desiree Pangilinan ,  Thomas Craig Masterman

IPC: C12N9/42 ,  C12P19/02 ,  C12P19/14

Abstract: The present invention relates to compositions comprising an aglycosylated polypeptide having cellobiase activity, and methods for producing and using the same.

公开(公告)号：US10377999B2

公开(公告)日：2019-08-13

申请号：US14782205

申请日：2015-09-25

Applicant: XYLECO, INC.

Inventor： Marshall Medoff ,  Natasha Kreder ,  James J. Lynch ,  Sean Landry ,  Aiichiro Yoshida ,  Desiree Pangilinan ,  Thomas Craig Masterman

IPC: C12N9/42 ,  C12P19/02 ,  C12P19/14

Abstract: The present invention relates to mixtures comprising a polypeptide or a plurality of polypeptides having biomass-degrading activity that is solubilized from an inclusion body, and retaining biomass-degrading activity, and methods for producing and using the same. The invention described herein provides methods for increasing the yield of recombinant protein with biomass-degrading activity that can be isolated from host cells.

公开(公告)号：US20180010088A1

公开(公告)日：2018-01-11

申请号：US15031439

申请日：2016-03-30

Applicant: XYLECO, INC.

Inventor： Marshall Medoff ,  Thomas Craig Masterman ,  Aiichiro Yoshida ,  Jaewoong Moon ,  Christopher G. Bergeron ,  James J. Lynch

IPC: C12N1/14 ,  C12P19/02 ,  C12N9/42 ,  C12P19/14 ,  C12N1/38

CPC classification number: C12N1/14 ,  C12N1/22 ,  C12N1/38 ,  C12N9/2437 ,  C12P19/02 ,  C12P19/14 ,  C12Y302/01004 ,  Y02E50/16 ,  Y02E50/17

Abstract: The present invention relates to compositions to induce production of proteins, e.g., enzymes, e.g., amylases or biomass degrading enzymes in a host cell, and methods for increasing the yield of the proteins, e.g., enzymes produced. Such compositions comprise a caramelized sugar product. The methods described herein can also be used to enhance processing of biomass materials, e.g., to produce sugar products.