公开(公告)号：US20240360220A1

公开(公告)日：2024-10-31

申请号：US18647843

申请日：2024-04-26

Applicant: Xencor, Inc.

Inventor： Gregory Moore ,  John R. Desjarlais ,  Bhavika R. Patel

IPC: C07K16/28

CPC classification number: C07K16/283 ,  C07K2317/51 ,  C07K2317/522 ,  C07K2317/524 ,  C07K2317/526 ,  C07K2317/53 ,  C07K2317/55

Abstract: Provided herein are multimeric proteins that reduce the promiscuous pairing of monomers of the multimeric protein and/or promote the proper pairing of monomers of the multimeric proteins, as well as methods of using such multimeric proteins.