公开(公告)号：US20250043001A1

公开(公告)日：2025-02-06

申请号：US18605762

申请日：2024-03-14

Applicant: Xencor, Inc.

Inventor： Gregory Moore ,  Viralkumar Rameshkumar Davra ,  Dong Hyun Nam ,  Veronica Gusti Zeng ,  Michael Hedvat ,  Jing Qi ,  Rumana Rashid ,  Patrick Arpp ,  Ernesto Delgado ,  ChaoFang Tan ,  Heather Preciado Jimenez ,  Charles G. Bakhit ,  Juan Diaz

IPC: C07K16/28 ,  C07K16/30 ,  C07K16/46

Abstract: Provided herein are novel anti-CD28 x anti-STEAP1 and anti-CD28 x anti-CEACAM5 antibodies and methods of using such antibodies for the treatment of related cancers.