Compositions useful as a cannabinoid receptor probe
    2.
    发明授权
    Compositions useful as a cannabinoid receptor probe 失效
    可用作大麻素受体探针的组合物

    公开(公告)号:US5440052A

    公开(公告)日:1995-08-08

    申请号:US103883

    申请日:1993-08-06

    IPC分类号: C07D311/88 C07D311/80

    CPC分类号: C07D311/88

    摘要: A composition of matter, comprising a cannabinol compound having the structure ##STR1## wherein, Q is --C(R.sup.1) (Y.sup.1)--(CH.sub.2).sub.n ----Z.sup.1 ; R.sup.1 is --H or --CH.sub.3 ; Y.sup.1 is --CH.sub.3 or Y.sup.2 ; Y.sup.2 is --N.sub.3 or --NCS; n is 4 or 6; Z.sup.1 is --H, when Y.sup.1 is Y.sup.2, or is Z.sup.2, when Y.sup.1 is --CH.sub.3 ; and Z.sup.2 is --N.sub.3 or --NCS.This composition has good binding affinity to the cannabinoid receptor and therefore, is useful as a receptor probe.

    摘要翻译: 一种物质组合物,其包含具有结构式的大麻酚化合物,其中Q为-C(R 1)(Y 1) - (CH 2)n -Z 1; R1是-H或-CH3; Y1是-CH3或Y2; Y2为-N3或-NCS; n为4或6; Z1为-H,Y1为Y2时为Z2,Y1为-CH3时为Z2; Z2为-N3或-NCS。 该组合物对大麻素受体具有良好的结合亲和力,因此可用作受体探针。