公开(公告)号：US08260556B2

公开(公告)日：2012-09-04

申请号：US12196132

申请日：2008-08-21

申请人： Robert Likuski ,  Roger Walker ,  Yabin Lu

发明人： Robert Likuski ,  Roger Walker ,  Yabin Lu

IPC分类号： G01N33/50 ,  G01N33/481

CPC分类号： G01N33/723 ,  G01N33/721

摘要： The ratio of analytes is determined directly from the responses of the analytes using a conversion method. Individual analyte responses are obtained by using a selected measuring technique, and these individual responses are used as the independent variables in a conversion method. The dependent variable of conversion method is the desired analyte ratio. The resulting conversion method is then used to directly calculate the desired ratio of analytes as a function of the measured responses. No intermediate conversions, such as using a calibration curve to convert individual measured analyte responses to concentration values, are needed to obtain the desired ratio.

摘要翻译： 分析物的比例直接由使用转化方法的分析物的反应确定。 通过使用选定的测量技术获得单个分析物响应，并且将这些单独的反应用作转化方法中的独立变量。 转化方法的因变量是所需的分析物比例。 然后使用所得的转化方法直接计算作为测量响应的函数的分析物的期望比例。 不需要中间转换，例如使用校正曲线将单个测量的分析物反应转化为浓度值，以获得所需的比例。

公开(公告)号：US20120084010A1

公开(公告)日：2012-04-05

申请号：US12895626

申请日：2010-09-30

申请人： Yabin Lu ,  Roger Walker

发明人： Yabin Lu ,  Roger Walker

IPC分类号： G06F19/00 ,  G06F17/10 ,  G01N33/48

CPC分类号： G01N33/723

摘要： Methods, systems, and apparatus for accurately determining a proportion (ratio) of two analytes is provided, as well as provide a concentration of a first analyte from a determined concentration of a second analyte and from a proportion of the analytes to each other. In one aspect, a surface model (called a “dose surface” herein) relating the concentrations of the two analytes to the proportion can be used to obtain accurate values for one of the variables (e.g. a concentration or the proportion) when the other two variables have previously been obtained. The dose surface can be a three-dimensional surface and be non-linear. The dose surface model can include multiple regression functions. For example, measured responses can be individually converted to concentrations using two dose-response curves, and the concentrations can be input to a dose surface function to obtain the proportion.

摘要翻译： 提供用于精确测定两种分析物的比例（比例）的方法，系统和装置，以及从确定的第二分析物浓度和一部分分析物彼此提供第一分析物的浓度。 在一个方面，可以使用将两种分析物的浓度与比例相关联的表面模型（称为“剂量表面”），以便当其他两个分析物之间的一个变量（例如浓度或比例）获得准确的值 以前已经获得了变量。 剂量表面可以是三维表面并且是非线性的。 剂量表面模型可以包括多个回归函数。 例如，测量的反应可以使用两个剂量 - 反应曲线单独转化为浓度，并且可以将浓度输入到剂量表面函数以获得比例。

公开(公告)号：US20100049444A1

公开(公告)日：2010-02-25

申请号：US12196132

申请日：2008-08-21

申请人： Robert Likuski ,  Roger Walker ,  Yabin Lu

发明人： Robert Likuski ,  Roger Walker ,  Yabin Lu

IPC分类号： G06F19/00 ,  G01N33/68 ,  G01N33/72

CPC分类号： G01N33/723 ,  G01N33/721

摘要： The ratio of analytes is determined directly from the responses of the analytes using a conversion method. Individual analyte responses are obtained by using a selected measuring technique, and these individual responses are used as the independent variables in a conversion method. The dependent variable of conversion method is the desired analyte ratio. The resulting conversion method is then used to directly calculate the desired ratio of analytes as a function of the measured responses. No intermediate conversions, such as using a calibration curve to convert individual measured analyte responses to concentration values, are needed to obtain the desired ratio.

摘要翻译： 分析物的比例直接由使用转化方法的分析物的反应确定。 通过使用选定的测量技术获得单个分析物响应，并且将这些单独的反应用作转化方法中的独立变量。 转化方法的因变量是所需的分析物比例。 然后使用所得的转化方法直接计算作为测量响应的函数的分析物的期望比例。 不需要中间转换，例如使用校正曲线将单个测量的分析物反应转化为浓度值，以获得所需的比例。

公开(公告)号：US08620590B2

公开(公告)日：2013-12-31

申请号：US12895626

申请日：2010-09-30

申请人： Yabin Lu ,  Roger Walker

发明人： Yabin Lu ,  Roger Walker

IPC分类号： G06F7/00

CPC分类号： G01N33/723

摘要： Methods, systems, and apparatus for accurately determining a proportion (ratio) of two analytes is provided, as well as provide a concentration of a first analyte from a determined concentration of a second analyte and from a proportion of the analytes to each other. In one aspect, a surface model (called a “dose surface” herein) relating the concentrations of the two analytes to the proportion can be used to obtain accurate values for one of the variables (e.g. a concentration or the proportion) when the other two variables have previously been obtained. The dose surface can be a three-dimensional surface and be non-linear. The dose surface model can include multiple regression functions. For example, measured responses can be individually converted to concentrations using two dose-response curves, and the concentrations can be input to a dose surface function to obtain the proportion.

摘要翻译： 提供用于精确测定两种分析物的比例（比例）的方法，系统和装置，以及从确定的第二分析物浓度和一部分分析物彼此提供第一分析物的浓度。 在一个方面，可以使用将两种分析物的浓度与比例相关联的表面模型（称为“剂量表面”），以便当其他两个分析物之间的一个变量（例如浓度或比例）获得准确的值 以前已经获得了变量。 剂量表面可以是三维表面并且是非线性的。 剂量表面模型可以包括多个回归函数。 例如，测量的反应可以使用两个剂量 - 反应曲线单独转化为浓度，并且可以将浓度输入到剂量表面函数以获得比例。

公开(公告)号：US4709630A

公开(公告)日：1987-12-01

申请号：US8086

申请日：1987-01-21

申请人： David R. G. Wilkins ,  Reginald D. Brooker ,  Roger Walker ,  Harry Powell

发明人： David R. G. Wilkins ,  Reginald D. Brooker ,  Roger Walker ,  Harry Powell

IPC分类号： B41J7/34 ,  B41J29/38 ,  B41J1/46

CPC分类号： B41J7/34 ,  B41J29/38

摘要： Apparatus for printing any line of characters comprises printing wheels on a common shaft, the wheels on the shaft together defining a printing line over a hammer. Each printing wheel is rotated by a respective stepping motor through a respective setting wheel. An aligner bar is inserted into notches in the wheels, prior to printing, to verify the alignment of the characters in printing position. The stepping motors are bi-directional and take the shortest path from a preceding printing position to the next printing position. The pulsing frequency may be ramped to give a higher stepping rate in the intermediate portion of each printing wheel movement.

摘要翻译： 用于打印任何字符行的装置包括在公共轴上的印刷轮，所述轴上的轮一起在锤上定义印刷线。 每个印刷轮由相应的步进电机通过相应的调整轮旋转。 在打印之前，将对准器条插入车轮中的凹口中，以验证打印位置中字符的对齐。 步进电机是双向的，并且从前一个打印位置到下一个打印位置的最短路径。 脉冲频率可以倾斜以在每个印刷轮运动的中间部分中提供更高的步进率。

公开(公告)号：US4341299A

公开(公告)日：1982-07-27

申请号：US147788

申请日：1980-05-08

申请人： Roger Walker ,  Alan Holdsworth

发明人： Roger Walker ,  Alan Holdsworth

IPC分类号： B65H31/30 ,  B65G47/26

CPC分类号： B65H31/3081 ,  B65H2701/1912

摘要： In apparatus for conveying successive stacks of sheets to a station at which an operation is to be performed on the stack, the sheets are advanced by pushing elements (14) to the station, at which a resilient finger (17) projects through a slot (16) in the track. The finger (17) aligns the leading edges of the sheets in the stack. When the stack of sheets is to be advanced, a slide (20) retracts. The finger (17) is pivotally mounted on the slide and its upper inclined edge engages the bottom rear corner of the slot when the slide is retracted, causing the finger to sink below the track until the slide is returned in time for the alignment of the next stack.

摘要翻译： 在用于将连续堆叠的纸张传送到要在纸张上执行操作的工位的装置中，通过将元件（14）推动到工位，使弹性手指（17）突出通过槽（ 16）在轨道上。 手指（17）对齐堆叠中的片材的前边缘。 当纸叠要前进时，滑块（20）缩回。 手指（17）枢转地安装在滑块上，并且当滑动件缩回时，其上倾斜边缘接合槽的底部后角，导致手指沉没在轨道下方，直到滑块及时返回以使对准 下一堆

公开(公告)号：US07740028B1

公开(公告)日：2010-06-22

申请号：US11307122

申请日：2006-01-24

申请人： Jeffrey M. Wilson ,  Michael R. Kessler ,  Roger Walker

发明人： Jeffrey M. Wilson ,  Michael R. Kessler ,  Roger Walker

IPC分类号： F16L55/16

CPC分类号： F16L55/1612 ,  F16L55/168 ,  F16L55/1705

摘要： A composite plug system and a process to repair a hole in a tubular pipe. The process includes the steps of inserting a fastener through an opening in an oblong inner plate having an elongated diameter and a shorter diameter. The oblong plate is inserted into the pipe hole wherein the elongated diameter is greater than a diameter of the pipe hole and wherein the shorter diameter is less than the pipe hole diameter so that the oblong plate is within the tubular pipe beneath the hole. An initially liquid adhesive filler is applied over the oblong inner plate over the pipe hole. An outer plate having a central opening and a diameter larger than the pipe hole diameter is affixed over the pipe hole so that the central opening receives the fastener. The outer plate is secured to the oblong inner plate and the tubular pipe with the fastener until the adhesive filler solidifies. After the filler solidifies, the oblong plate and the outer plate are structurally bonded to the pipe wall through adhesion.

摘要翻译： 一种复合插塞系统和一种维修管状管孔的方法。 该方法包括以下步骤：将紧固件穿过具有细长直径和较短直径的长方形内板中的开口。 长管板插入管孔中，其中细长直径大于管孔的直径，并且其中较短直径小于管孔直径，使得长形板位于孔下方的管状管内。 首先将液体粘合剂填料施加在管孔上方的长方形内板上。 具有中心开口并且直径大于管孔直径的外板被固定在管孔上，使得中心开口接收紧固件。 外板用紧固件固定到长方形内板和管状管件上，直到粘合剂填料固化。 在填料凝固后，长方形板和外板通过粘合结构地结合到管壁上。

公开(公告)号：US20090324397A1

公开(公告)日：2009-12-31

申请号：US11671933

申请日：2007-02-06

申请人： Philip Caruso ,  Dwight Davidson ,  Yang Liu ,  William Parker ,  Roger Walker ,  Sivaraman Vedhagiri

发明人： Philip Caruso ,  Dwight Davidson ,  Yang Liu ,  William Parker ,  Roger Walker ,  Sivaraman Vedhagiri

IPC分类号： F01D25/08

CPC分类号： F01D9/065 ,  F02C6/08 ,  F05D2260/231

摘要： A gas turbine engine is provided comprising a compressor with an insulated cooling circuit. The compressor comprises a compressor casing having a compression chamber and at least one stator and at least one rotor disposed in the compression chamber, the at least one stator comprising a stator body having a plurality of tubes for transporting cooling air through passages in the stator body into the compression chamber. The plurality of tubes are surrounded by an air gap for insulating the tubes from the stator body.

摘要翻译： 提供一种燃气涡轮发动机，其包括具有绝缘冷却回路的压缩机。 压缩机包括压缩机壳体，其具有压缩室和至少一个定子以及设置在压缩室中的至少一个转子，所述至少一个定子包括具有多个管的定子体，所述多个管用于将冷却空气通过定子体中的通道传送 进入压缩室。 多个管被气隙包围，用于使管与定子体绝缘。

公开(公告)号：US08603828B2

公开(公告)日：2013-12-10

申请号：US12941738

申请日：2010-11-08

申请人： Roger Walker ,  Benedicte Jardin

发明人： Roger Walker ,  Benedicte Jardin

IPC分类号： G01N33/72 ,  G01N33/543 ,  A61K35/14

CPC分类号： G01N33/721 ,  C07K16/18 ,  C07K2317/34 ,  C07K2317/92 ,  G01N33/531 ,  G01N33/582 ,  G01N33/723 ,  Y10T436/101666 ,  Y10T436/25125

摘要： Hemoglobin, its variants, and glycated forms of each are determined individually in a multiplex assay that permits correction of the measured level of HbA1c to account for glycated variants and other factors related to the inclusion of the variants in the sample. New antibodies that are particularly well adapted to the multiplex assay are also provided.

公开(公告)号：US08182205B2

公开(公告)日：2012-05-22

申请号：US11671933

申请日：2007-02-06

申请人： Philip Caruso ,  Dwight Davidson ,  Yang Liu ,  William Parker ,  Roger Walker ,  Sivaraman Vedhagiri

发明人： Philip Caruso ,  Dwight Davidson ,  Yang Liu ,  William Parker ,  Roger Walker ,  Sivaraman Vedhagiri

IPC分类号： F04D31/00

CPC分类号： F01D9/065 ,  F02C6/08 ,  F05D2260/231

摘要： A gas turbine engine is provided comprising a compressor with an insulated cooling circuit. The compressor comprises a compressor casing having a compression chamber and at least one stator and at least one rotor disposed in the compression chamber, the at least one stator comprising a stator body having a plurality of tubes for transporting cooling air through passages in the stator body into the compression chamber. The plurality of tubes are surrounded by an air gap for insulating the tubes from the stator body.

摘要翻译： 提供一种燃气涡轮发动机，其包括具有绝缘冷却回路的压缩机。 压缩机包括压缩机壳体，其具有压缩室和至少一个定子以及设置在压缩室中的至少一个转子，所述至少一个定子包括具有多个管的定子体，所述多个管用于将冷却空气通过定子体中的通道传送 进入压缩室。 多个管被气隙包围，用于使管与定子体绝缘。