公开(公告)号：US20120226328A1

公开(公告)日：2012-09-06

申请号：US13466431

申请日：2012-05-08

申请人： Yanting Dong ,  Yinghong Yu ,  Jiang Ding ,  Scott A. Meyer ,  Xuan Wei ,  Michael John Stucky

发明人： Yanting Dong ,  Yinghong Yu ,  Jiang Ding ,  Scott A. Meyer ,  Xuan Wei ,  Michael John Stucky

IPC分类号： A61N1/365 ,  A61N1/37

CPC分类号： A61N1/3627 ,  A61N1/36585 ,  A61N1/3684

摘要： Systems and methods involve determination of CRT parameters using a number of CRT optimization processes. Each CRT optimization process attempts to return recommended parameters. The CRT parameters are determined based on the recommended parameters returned by one or more of the CRT optimization processes. The CRT optimization processes may be sequentially implemented and the CRT parameters may be determined based on the recommended parameters returned by a first CRT optimization process to return recommended parameters. The CRT parameters may be determined based on a combination of the recommended parameters returned. The CRT optimization processes implemented may be selected from available CRT optimization processes based on patient conditions.

摘要翻译： 系统和方法涉及使用多个CRT优化过程来确定CRT参数。 每个CRT优化过程都会尝试返回推荐的参数。 CRT参数根据一个或多个CRT优化过程返回的推荐参数来确定。 可以顺序地实施CRT优化过程，并且可以基于由第一CRT优化过程返回的推荐参数来返回推荐参数来确定CRT参数。 可以基于返回的推荐参数的组合来确定CRT参数。 可以根据患者条件从可用的CRT优化过程中选择实现的CRT优化处理。

公开(公告)号：US20100023078A1

公开(公告)日：2010-01-28

申请号：US11338935

申请日：2006-01-25

申请人： Yanting Dong ,  Yinghong Yu ,  Jiang Ding ,  Scott A. Meyer ,  Xuan Wei ,  Michael John Stucky

发明人： Yanting Dong ,  Yinghong Yu ,  Jiang Ding ,  Scott A. Meyer ,  Xuan Wei ,  Michael John Stucky

IPC分类号： A61N1/00

CPC分类号： A61N1/3627 ,  A61N1/36585 ,  A61N1/3684

摘要： Systems and methods involve determination of CRT parameters using a number of CRT optimization processes. Each CRT optimization process attempts to return recommended parameters. The CRT parameters are determined based on the recommended parameters returned by one or more of the CRT optimization processes. The CRT optimization processes may be sequentially implemented and the CRT parameters may be determined based on the recommended parameters returned by a first CRT optimization process to return recommended parameters. The CRT parameters may be determined based on a combination of the recommended parameters returned. The CRT optimization processes implemented may be selected from available CRT optimization processes based on patient conditions.

摘要翻译： 系统和方法涉及使用多个CRT优化过程来确定CRT参数。 每个CRT优化过程都会尝试返回推荐的参数。 CRT参数根据一个或多个CRT优化过程返回的推荐参数来确定。 可以顺序地实施CRT优化过程，并且可以基于由第一CRT优化过程返回的推荐参数来返回推荐参数来确定CRT参数。 可以基于返回的推荐参数的组合来确定CRT参数。 可以根据患者条件从可用的CRT优化过程中选择实现的CRT优化处理。

公开(公告)号：US08175703B2

公开(公告)日：2012-05-08

申请号：US11338935

申请日：2006-01-25

申请人： Yanting Dong ,  Yinghong Yu ,  Jiang Ding ,  Scott A. Meyer ,  Xuan Wei ,  Michael John Stucky

发明人： Yanting Dong ,  Yinghong Yu ,  Jiang Ding ,  Scott A. Meyer ,  Xuan Wei ,  Michael John Stucky

IPC分类号： A61N1/362

CPC分类号： A61N1/3627 ,  A61N1/36585 ,  A61N1/3684

摘要： Systems and methods involve determination of CRT parameters using a number of CRT optimization processes. Each CRT optimization process attempts to return recommended parameters. The CRT parameters are determined based on the recommended parameters returned by one or more of the CRT optimization processes. The CRT optimization processes may be sequentially implemented and the CRT parameters may be determined based on the recommended parameters returned by a first CRT optimization process to return recommended parameters. The CRT parameters may be determined based on a combination of the recommended parameters returned. The CRT optimization processes implemented may be selected from available CRT optimization processes based on patient conditions.

摘要翻译： 系统和方法涉及使用多个CRT优化过程来确定CRT参数。 每个CRT优化过程都会尝试返回推荐的参数。 CRT参数根据一个或多个CRT优化过程返回的推荐参数来确定。 可以顺序地实施CRT优化过程，并且可以基于由第一CRT优化过程返回的推荐参数来返回推荐参数来确定CRT参数。 可以基于返回的推荐参数的组合来确定CRT参数。 可以根据患者条件从可用的CRT优化过程中选择实现的CRT优化处理。

公开(公告)号：US07555340B2

公开(公告)日：2009-06-30

申请号：US11097460

申请日：2005-04-01

申请人： Yanting Dong ,  Jiang Ding ,  Douglas R. Daum ,  Scott A. Meyer ,  Yinghong Yu

发明人： Yanting Dong ,  Jiang Ding ,  Douglas R. Daum ,  Scott A. Meyer ,  Yinghong Yu

IPC分类号： A61N1/365

CPC分类号： A61N1/368 ,  A61N1/3682 ,  A61N1/371

摘要： A method and system for determining an optimum atrioventricular delay (AVD) interval and/or ventriculo-ventricular delay (VVD) intervals for delivering ventricular resynchronization pacing in an atrial tracking or atrial sequential pacing mode. Evoked response electrograms recorded at different AVD and VVD intervals are used to determine the extent of paced and intrinsic activation.

摘要翻译： 一种用于确定用于在心房跟踪或心房顺序起搏模式中递送心室再同步起搏的最佳房室延迟（AVD）间隔和/或心室 - 心室延迟（VVD）间隔的方法和系统。 以不同的AVD和VVD间隔记录的诱发反应电图用于确定起搏和内在激活的程度。

公开(公告)号：US08078276B2

公开(公告)日：2011-12-13

申请号：US12494628

申请日：2009-06-30

申请人： Yanting Dong ,  Jiang Ding ,  Douglas R. Daum ,  Scott A. Meyer ,  Yinghong Yu

发明人： Yanting Dong ,  Jiang Ding ,  Douglas R. Daum ,  Scott A. Meyer ,  Yinghong Yu

IPC分类号： A61N1/365

CPC分类号： A61N1/368 ,  A61N1/3682 ,  A61N1/371

摘要： A method and system for determining an optimum atrioventricular delay (AVD) interval and/or ventriculo-ventricular delay (VVD) intervals for delivering ventricular resynchronization pacing in an atrial tracking or atrial sequential pacing mode. Evoked response electrograms recorded at different AVD and VVD intervals are used to determine the extent of paced and intrinsic activation.

摘要翻译： 一种用于确定用于在心房跟踪或心房顺序起搏模式中递送心室再同步起搏的最佳房室延迟（AVD）间隔和/或心室 - 心室延迟（VVD）间隔的方法和系统。 以不同的AVD和VVD间隔记录的诱发反应电图用于确定起搏和内在激活的程度。

公开(公告)号：US20090264949A1

公开(公告)日：2009-10-22

申请号：US12494628

申请日：2009-06-30

申请人： Yanting Dong ,  Jiang Ding ,  Douglas R. Daum ,  Scott A. Meyer ,  Yinghong Yu

发明人： Yanting Dong ,  Jiang Ding ,  Douglas R. Daum ,  Scott A. Meyer ,  Yinghong Yu

IPC分类号： A61N1/365

CPC分类号： A61N1/368 ,  A61N1/3682 ,  A61N1/371

摘要： A method and system for determining an optimum atrioventricular delay (AVD) interval and/or ventriculo-ventricular delay (VVD) intervals for delivering ventricular resynchronization pacing in an atrial tracking or atrial sequential pacing mode. Evoked response electrograms recorded at different AVD and VVD intervals are used to determine the extent of paced and intrinsic activation.

摘要翻译： 一种用于确定用于在心房跟踪或心房顺序起搏模式中递送心室再同步起搏的最佳房室延迟（AVD）间隔和/或心室 - 心室延迟（VVD）间隔的方法和系统。 以不同的AVD和VVD间隔记录的诱发反应电图用于确定起搏和内在激活的程度。

公开(公告)号：US08620430B2

公开(公告)日：2013-12-31

申请号：US11479877

申请日：2006-06-30

申请人： Shantha Arcot-Krishnamurthy ,  Michael John Stucky ,  Yinghong Yu ,  Jiang Ding

发明人： Shantha Arcot-Krishnamurthy ,  Michael John Stucky ,  Yinghong Yu ,  Jiang Ding

IPC分类号： A61N1/362

CPC分类号： A61N1/36585 ,  A61N1/36514 ,  A61N1/36535 ,  A61N1/36542 ,  A61N1/36557 ,  A61N1/36578 ,  A61N1/36592

摘要： Systems and methods for selection of electrodes and related pacing configuration parameters used to pace a heart chamber are described. A change in the hemodynamic state of a patient is detected. Responsive to the detected change, a distribution of an electrical, mechanical, or electromechanical parameter related to contractile function of a heart chamber with respect to locations of multiple electrodes disposed within the heart chamber is determined. A pacing output configuration, including one or more electrodes of the multiple electrodes, is selected and the heart chamber is paced using the selected pacing output configuration.

公开(公告)号：US20080004667A1

公开(公告)日：2008-01-03

申请号：US11479877

申请日：2006-06-30

申请人： Shantha Arcot-Krishnamurthy ,  Michael John Stucky ,  Yinghong Yu ,  Jiang Ding

发明人： Shantha Arcot-Krishnamurthy ,  Michael John Stucky ,  Yinghong Yu ,  Jiang Ding

IPC分类号： A61N1/00

CPC分类号： A61N1/36585 ,  A61N1/36514 ,  A61N1/36535 ,  A61N1/36542 ,  A61N1/36557 ,  A61N1/36578 ,  A61N1/36592

摘要： Systems and methods for selection of electrodes and related pacing configuration parameters used to pace a heart chamber are described. A change in the hemodynamic state of a patient is detected. Responsive to the detected change, a distribution of an electrical, mechanical, or electromechanical parameter related to contractile function of a heart chamber with respect to locations of multiple electrodes disposed within the heart chamber is determined. A pacing output configuration, including one or more electrodes of the multiple electrodes, is selected and the heart chamber is paced using the selected pacing output configuration.

摘要翻译： 描述了用于选择电极的系统和方法以及用于调节心室的相关起搏配置参数。 检测患者的血液动力学状态的变化。 响应于检测到的变化，确定与心室的收缩功能相关的电，机械或机电参数相对于设置在心室内的多个电极的位置的分布。 选择包括多个电极中的一个或多个电极的起搏输出配置，并且使用所选择的起搏输出配置来起搏心室。

公开(公告)号：US08725255B2

公开(公告)日：2014-05-13

申请号：US11601216

申请日：2006-11-17

申请人： Shantha Arcot-Krishnamurthy ,  Yi Zhang ,  Jiang Ding ,  Yinghong Yu ,  Yanting Dong

发明人： Shantha Arcot-Krishnamurthy ,  Yi Zhang ,  Jiang Ding ,  Yinghong Yu ,  Yanting Dong

IPC分类号： A61N1/365 ,  A61N1/362

CPC分类号： A61N1/3627 ,  A61B5/04011 ,  A61B5/0452 ,  A61N1/365 ,  A61N1/36535 ,  A61N1/36542

摘要： Systems and methods provide for pacing a heart to improve pumping efficiency of the heart, such as by producing a cardiac fusion response for patient's subject to cardiac resynchronization therapy. A pacing parameter, such as an A-V delay, V-V delay, lead/electrode configuration or vector, is adjusted and a cardiac signal vector representative of all or a portion of one or more cardiac activation sequences is monitored during pacing parameter adjustment. A change in a characteristic of the cardiac signal vector is detected in response to an adjusted pacing parameter, the change indicative of a cardiac fusion response. A pacing therapy may be delivered to produce the cardiac fusion response using the adjusted pacing parameter.

摘要翻译： 系统和方法提供心脏起搏以改善心脏的泵送效率，例如通过为患者进行心脏再同步治疗产生心脏融合反应。 调整起搏参数，例如A-V延迟，V-V延迟，引线/电极配置或载体，并且在起搏参数调整期间监测表示一个或多个心脏激活序列的全部或一部分的心脏信号载体。 响应于调整的起搏参数，指示心脏融合反应的变化来检测心脏信号载体的特性变化。 可以使用调整的起搏参数来递送起搏治疗以产生心脏融合反应。

公开(公告)号：US20060224198A1

公开(公告)日：2006-10-05

申请号：US11097460

申请日：2005-04-01

申请人： Yanting Dong ,  Jiang Ding ,  Douglas Daum ,  Scott Meyer ,  Yinghong Yu

发明人： Yanting Dong ,  Jiang Ding ,  Douglas Daum ,  Scott Meyer ,  Yinghong Yu

IPC分类号： A61N1/362

CPC分类号： A61N1/368 ,  A61N1/3682 ,  A61N1/371

摘要： A method and system are described for determining an optimum atrioventricular delay (AVD) interval and/or ventriculo-ventricular delay (VVD) intervals for delivering ventricular resynchronization pacing in an atrial tracking or atrial sequential pacing mode. Evoked response electrograms recorded at different AVD and VVD intervals are used to determine the extent of paced and intrinsic activation.

摘要翻译： 描述了用于确定用于在心房跟踪或心房顺序起搏模式中递送心室再同步起搏的最佳房室延迟（AVD）间隔和/或心室 - 心室延迟（VVD）间隔的方法和系统。 以不同的AVD和VVD间隔记录的诱发反应电图用于确定起搏和内在激活的程度。