公开(公告)号：US20090130215A1

公开(公告)日：2009-05-21

申请号：US11912463

申请日：2006-04-26

申请人： Yasushi OCHIAI ,  Yasuhiro MATSUI

发明人： Yasushi OCHIAI ,  Yasuhiro MATSUI

IPC分类号： A61K9/14 ,  A61K31/4439 ,  A61P3/10

CPC分类号： A61K9/1652 ,  A61K9/0056 ,  A61K9/1611 ,  A61K9/1623 ,  A61K31/155 ,  Y10S514/866

摘要： A granular preparation containing a biguanide compound and a solidification-preventive agent does not solidify during storage and can avoid the difficulty in dosing.

摘要翻译： 含有双胍化合物和防固化剂的颗粒剂在储存期间不固化，并且可以避免给药困难。

公开(公告)号：US20190290579A1

公开(公告)日：2019-09-26

申请号：US16220619

申请日：2018-12-14

申请人： Mitsuhiro MATONO ,  Hirohisa KOBAYASHI ,  Yuki IKEDA ,  Yasushi OCHIAI

发明人： Mitsuhiro MATONO ,  Hirohisa KOBAYASHI ,  Yuki IKEDA ,  Yasushi OCHIAI

IPC分类号： A61K9/00 ,  A61K9/28

摘要： The present invention provides an orally disintegrating tablet with improved photostability of a medicament unstable to light. The orally disintegrating tablet has an inner core and an outer layer that covers the surface of the inner core, wherein the inner core contains the medicament unstable to light and the outer layer contains a light-absorbing substance such as Red No. 2, Red No. 3, Yellow No. 4, Yellow No. 5, Blue No. 1, Red No. 3 aluminum lake, Yellow No. 4 aluminum lake, Yellow No. 5 aluminum lake, Blue No. 1 aluminum lake, Blue No. 2 aluminum lake, red ferric oxide, yellow ferric oxide, black iron oxide, carmine, or sodium copper chlorophyllin.