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公开(公告)号:US20210363495A1
公开(公告)日:2021-11-25
申请号:US17382500
申请日:2021-07-22
Applicant: Yeda Research and Development Co. Ltd.
Inventor: Yaqub HANNA , Noa NOVERSHTERN , Tom Haim SHANI , Sergey VIUKOV , Rada MASSARWA , Jonathan BAYERL , Muneef AYYASH
IPC: C12N5/074
Abstract: A culture medium comprising a WNT inhibitor, a SRC inhibitor and a protein kinase C (PKC) inhibitor is disclosed. The medium is devoid of an amount of GSK3beta inhibitor that increases beta-catenin translocation to the nucleus of a pluripotent stem cell being cultured in the culture medium. Uses thereof are also disclosed.