公开(公告)号：US10072044B2

公开(公告)日：2018-09-11

申请号：US15180031

申请日：2016-06-12

Applicant: Yeda Research and Development Co. Ltd.

Inventor： Michal Schwartz-Eisenbach ,  Matityahu Fridkin ,  Michal Cardon-Yaakov

IPC: A61K9/00 ,  A61K38/00 ,  C07K7/06 ,  C07K7/64

CPC classification number: C07K7/06 ,  A61K9/0053 ,  A61K38/00 ,  C07K7/64

Abstract: The present application provides synthetic modified peptides of five to seven natural or non-natural amino acids as well as pharmaceutical compositions comprising them, for use in the treatment a disease or disorder presenting behavioral abnormalities associated with impairment of sensory gating function, depression or cognitive impairment, particularly schizophrenia and Alzheimer's disease.

公开(公告)号：US20150051151A1

公开(公告)日：2015-02-19

申请号：US14384685

申请日：2013-03-14

Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD AT THE WEIZMANN INSTITUTE OF SCIENCE

Inventor： Michal Eisenbach-Schwartz ,  Matityahu Fridkin ,  Michal Cardon-Yaakov

IPC: C07K7/64 ,  C07K7/06

CPC classification number: C07K7/06 ,  A61K9/0053 ,  A61K38/00 ,  C07K7/64

Abstract: The present application provides synthetic modified peptides of five to seven natural or non-natural amino acids as well as pharmaceutical compositions comprising them, for use in the treatment a disease or disorder presenting behavioral abnormalities associated with impairment of sensory gating function, depression or cognitive impairment, particularly schizophrenia and Alzheimer's disease.

Abstract translation: 本申请提供五至七个天然或非天然氨基酸的合成修饰肽以及包含它们的药物组合物，用于治疗与感觉门控功能障​​碍，抑郁症或认知障碍相关的行为异常的疾病或病症 ，特别是精神分裂症和阿尔茨海默病。

公开(公告)号：US09382293B2

公开(公告)日：2016-07-05

申请号：US14384685

申请日：2013-03-14

Applicant: Yeda Research and Development Co. Ltd.

Inventor： Michal Eisenbach-Schwartz ,  Matityahu Fridkin ,  Michal Cardon-Yaakov

IPC: C07K7/64 ,  C07K7/06 ,  A61K38/00

CPC classification number: C07K7/06 ,  A61K9/0053 ,  A61K38/00 ,  C07K7/64

Abstract: The present application provides synthetic modified peptides of five to seven natural or non-natural amino acids as well as pharmaceutical compositions comprising them, for use in the treatment a disease or disorder presenting behavioral abnormalities associated with impairment of sensory gating function, depression or cognitive impairment, particularly schizophrenia and Alzheimer's disease.

Abstract translation: 本申请提供五至七个天然或非天然氨基酸的合成修饰肽以及包含它们的药物组合物，用于治疗与感觉门控功能障​​碍，抑郁症或认知障碍相关的行为异常的疾病或病症 ，特别是精神分裂症和阿尔茨海默病。